PDF(Pubmed)
Abstract：
A 56-year-old female patient with a body weight of 60 kg was brought to the hospital with hematemesis and received one unit of packed red cells (PRCs) for this condition. After 30 min, the patient experienced tachycardia of 120 beats/min and an increased body temperature of 102°F. The patient had no relevant medical history of allergy or similar episodes in the past. The patient was not suffering from any coagulopathies or sickle cell anaemia, which is a prevalent condition in the region. The patient was receiving the PRC for the first time. After this event, the infusion was stopped and immediately injection meropenem, pantoprazole and ondansetron IV were administered. The patient\'s condition normalised after 6 h. No re-challenge was given after the recovery of the patient. Suspected ADR was analysed according to the World Health organization (WHO) causality assessment scale and the causality was \"Possible\". Meticulous monitoring and prompt therapy were provided. The patient was discharged after observing for 24 h. The adverse drug reaction was possibly caused due to the PRCs.
摘要：
一名56岁，体重60公斤的女性患者因呕血被送往医院，并接受了一个单位的红细胞（PRCs）治疗。30分钟后,患者经历了120次/分钟的心动过速和102°F的体温升高。患者过去无相关过敏史或类似发作史。病人没有任何凝血病或镰状细胞贫血,这是该地区的普遍状况。该患者是首次接受PRC治疗。在此事件之后,停止输液，立即注射美罗培南，给予泮托拉唑和昂丹司琼IV.6小时后患者病情恢复正常。患者康复后未进行再激发。根据世界卫生组织（WHO）因果关系评估量表对可疑ADR进行分析，因果关系为“可能”。提供了细致的监测和及时的治疗。患者观察24h后出院，药物不良反应可能是由于PRCs引起的。
