关键词: Anisakis pegreffii granuloma hepatic anisakidosis

Mesh : Male Animals Humans Aged Anisakis / genetics Phylogeny Liver Neoplasms / diagnosis Anisakiasis / diagnosis Larva

来  源:   DOI:10.3347/PHD.23055   PDF(Pubmed)

Abstract:
Extra-gastrointestinal anisakidosis is rare. We herein report an Anisakis pegreffii infection in a patient with hepatic anisakidosis diagnosed based on its molecular identification. A 71-year-old male patient had a hepatic tumor presenting as a low-density area of 20 mm in diameter in segment 6 of the liver on abdominal ultrasonography, computed tomography, and magnetic resonance imaging. The surgically resected pathological specimen revealed a necrotizing eosinophilic granuloma containing nematode larvae, possibly an Anisakis larva. Molecular and phylogenetic analysis demonstrated Anisakis larvae belonging to A. pegreffii. The present results will help identify and characterize unknown Anisakis species in histological sections.
摘要:
胃肠外ansakidosis是罕见的。我们在此报告了根据其分子鉴定诊断的肝anisakidosis患者的Anisakispegreffii感染。一名71岁的男性患者的肝肿瘤在腹部超声检查中表现为肝脏第6段直径为20mm的低密度区域。计算机断层扫描,和磁共振成像。手术切除的病理标本显示坏死性嗜酸性肉芽肿含有线虫幼虫,可能是异语幼虫。分子和系统发育分析表明,异株幼虫属于A.pegreffii。本结果将有助于在组织学切片中识别和表征未知的异尖异尖菌种。
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