PDF(Pubmed)
Abstract：
BACKGROUND: Most cancer patients undergoing chemotherapy develop anemia during their course of treatment. There is a need for early treatment for chemotherapy-induced anemia to prevent morbidity and mortality.
METHODS: This is a hospital-based study, conducted over one year and included 59 children who are known cases of hematological malignancy aged up to 18 years. Standard methods were used to measure micronutrients and complete blood count. Statistical analysis was done using SPSS for Windows, Version 15.0 (Released 2006; SPSS Inc., Chicago, United States).
RESULTS: The majority of subjects (n=21; 35.6%) were aged six to nine years with male dominance. Micronutrient deficiency and significant anemia were noted in 40-50% and 64.4% of cases, respectively. Both malignancy and blood indices showed no association with micronutrients.
CONCLUSIONS: Anemia with micronutrient deficiency is common in children with hematopoietic malignancies receiving chemotherapy. However, no significant association was noted between red cell indices and levels of micronutrients.
METHODS: This is a hospital-based study, conducted over one year and included 59 children who are known cases of hematological malignancy aged up to 18 years. Standard methods were used to measure micronutrients and complete blood count. Statistical analysis was done using SPSS for Windows, Version 15.0 (Released 2006; SPSS Inc., Chicago, United States).
RESULTS: The majority of subjects (n=21; 35.6%) were aged six to nine years with male dominance. Micronutrient deficiency and significant anemia were noted in 40-50% and 64.4% of cases, respectively. Both malignancy and blood indices showed no association with micronutrients.
CONCLUSIONS: Anemia with micronutrient deficiency is common in children with hematopoietic malignancies receiving chemotherapy. However, no significant association was noted between red cell indices and levels of micronutrients.
摘要：
背景：大多数接受化疗的癌症患者在治疗过程中会出现贫血。需要对化疗引起的贫血进行早期治疗以预防发病率和死亡率。
方法：这是一项以医院为基础的研究，进行了一年以上的研究，其中包括59名年龄在18岁以下的已知血液系统恶性肿瘤病例的儿童。使用标准方法测量微量营养素和全血细胞计数。使用SPSSforWindows进行统计分析，版本15.0（2006年发布；SPSSInc.，芝加哥,美国)。
结果：大多数受试者（n=21；35.6％）年龄在6至9岁之间，男性占优势。在40-50％和64.4％的病例中注意到微量营养素缺乏和严重贫血，分别。恶性肿瘤和血液指标均与微量营养素无关。
结论：在接受化疗的造血系统恶性肿瘤患儿中，伴有微量营养素缺乏的贫血是常见的。然而,红细胞指数和微量营养素水平之间没有显著关联.
方法：这是一项以医院为基础的研究，进行了一年以上的研究，其中包括59名年龄在18岁以下的已知血液系统恶性肿瘤病例的儿童。使用标准方法测量微量营养素和全血细胞计数。使用SPSSforWindows进行统计分析，版本15.0（2006年发布；SPSSInc.，芝加哥,美国)。
结果：大多数受试者（n=21；35.6％）年龄在6至9岁之间，男性占优势。在40-50％和64.4％的病例中注意到微量营养素缺乏和严重贫血，分别。恶性肿瘤和血液指标均与微量营养素无关。
结论：在接受化疗的造血系统恶性肿瘤患儿中，伴有微量营养素缺乏的贫血是常见的。然而,红细胞指数和微量营养素水平之间没有显著关联.
