PDF(Pubmed)
Abstract：
The emergence of new coronavirus variants and evidence of waning immunity offered by COVID-19 vaccines draw attention to the need for regular vaccination. Vaccine hesitancy is one of the top ten threats to global health. There is a dearth of knowledge on people\'s hesitancy to take regular COVID-19 vaccines. This study aimed to investigate the prevalence and determinants of hesitancy for regular COVID-19 vaccination. A population-based, random telephone survey was performed in Hong Kong in April 2022 (n = 1213). The age-standardized hesitancy rate for regular COVID-19 vaccines among Hong Kong adults was 39.4% (95% CI = 35.3-44.1%), exhibiting a sloping S-shape with age. Regression analyses revealed that females, young adults, self-perceived fair/bad health, low COVID-19 vaccine uptake, and believing there are better ways for prevention of infection were positive determinants of hesitancy for regular vaccination. Vaccine confidence, perceived severity and availability, trust in manufacturers and government, and civic duty inclination were negative determinants. Tailored vaccine promotions are needed for females, young adults, and people perceiving poor health and receiving fewer doses. Information on infection severity, vaccine availability, and trust in suppliers, products, and governments are key attitude-change facilitators to decrease hesitancy for regular COVID-19 vaccination and cope with future pandemics.
摘要：
新的冠状病毒变种的出现和COVID-19疫苗提供的免疫力下降的证据引起了人们对定期接种疫苗的必要性的关注。疫苗犹豫是全球健康面临的十大威胁之一。人们对定期接种COVID-19疫苗的犹豫缺乏了解。本研究旨在调查常规COVID-19疫苗接种犹豫的患病率和决定因素。以人口为基础，2022年4月在香港进行了随机电话调查(n=1213).香港成年人对常规COVID-19疫苗的年龄标准化犹豫率为39.4%(95%CI=35.3-44.1%)，随着年龄的增长呈现出倾斜的S形。回归分析显示，女性，年轻人,自我感知的正常/不良健康，COVID-19疫苗摄取低，相信有更好的预防感染的方法是对定期接种疫苗犹豫不决的积极决定因素。疫苗信心，感知的严重性和可用性，对制造商和政府的信任，和公民义务倾向是负面的决定因素。女性需要量身定制的疫苗促销，年轻人,和人们认为健康状况不佳，接受的剂量较少。关于感染严重程度的信息，疫苗可用性，以及对供应商的信任，产品,政府是态度转变的关键促进者，以减少对常规COVID-19疫苗接种的犹豫，并应对未来的大流行。
