PDF(Pubmed)
Abstract：
Metabolic syndrome (MetS) has become a significant public health concern globally. Weight managementis crucial in controlling MetS risk factors, making energy balance and weight loss strategies important in nutrition recommendations. Intermittent fasting (IF) has gained traction as a dietary approach for weight management and cardiovascular risk reduction. However, the effects of IF on cardiovascular risk factors have been inconsistent in previous studies. This review aims to summarize the effects of various types of IF on body mass index (BMI), glycemia, lipid profile, and blood pressure, while providing insights into their clinical implications. A comprehensive search of interventional studies and meta-analyses was conducted, and the results were analyzed. The findings indicate that different types of IF lead to mixed effects. Time-restricted eating (TRE) and alternate-day fasting (ADF) consistently showed decreases in BMI, while the outcomes of intermittent energy restriction (IER) were more uncertain. The effects of IF on glycemia and lipid profile were also variable, with TRE and ADF generally showing positive results. However, the impact of IER remained inconsistent. More research is needed to understand the long-term effects and optimal implementation of IF for managing metabolic syndrome and cardiovascular risk factors.
摘要：
代谢综合征（MetS）已成为全球重要的公共卫生问题。体重管理对于控制MetS风险因素至关重要，使能量平衡和减肥策略在营养建议中很重要。间歇性禁食（IF）已成为体重管理和降低心血管风险的饮食方法。然而,在以往的研究中,IF对心血管危险因素的影响不一致.本文旨在总结各种类型的IF对体重指数（BMI）的影响，血糖，血脂谱,还有血压,同时提供对其临床意义的见解。对干预研究和荟萃分析进行了全面搜索，并对结果进行了分析。结果表明，不同类型的IF会导致混合效应。限时进食（TRE）和隔日禁食（ADF）一致显示BMI下降，而间歇性能量限制（IER）的结果更不确定。IF对血糖和血脂的影响也是可变的，TRE和ADF通常显示出积极的结果。然而,IER的影响仍然不一致。需要更多的研究来了解IF管理代谢综合征和心血管危险因素的长期影响和最佳实施。
