关键词: Japanese Black acute phase protein diagnosis inflammatory marker serum amyloid A

来  源:   DOI:10.3390/vetsci10080528   PDF(Pubmed)

Abstract:
This study investigated the concentration of serum amyloid A (SAA), an acute phase protein, in Japanese Black cattle. Four practical trials were performed to evaluate the transition of SAA and sialic acid before and after dehorning, the relationship between the SAA concentration and other blood test parameters, the SAA dynamics in the diseased cattle, and the blood test results, including the SAA concentrations, of the two cases with a follow-up. The SAA concentration increased with dehorning but decreased 7 days after dehorning. The SAA concentration is positively correlated with the α-globulin, sialic acid, and fibrinogen concentrations and negatively correlated with the serum iron concentration. The SAA concentration in the deceased herd was significantly higher than that in the cured outcome herd. In addition, the SAA concentration in the cured group decreased significantly from the first test to retesting but increased significantly in the disuse group. Thus, SAA is a sensitive index of inflammation and a monitoring tool in Japanese Black cattle, and its measurement is considered useful in clinical practice.
摘要:
这项研究调查了血清淀粉样蛋白A(SAA)的浓度,一种急性期蛋白,日本黑牛进行了四个实际试验来评估SAA和唾液酸在去角之前和之后的转变,SAA浓度与其他血液检测参数之间的关系,病牛的SAA动力学,还有验血结果,包括SAA的浓度,在这两个案件中进行了随访。SAA浓度随着去角化而增加,但在去角化后7天下降。SAA浓度与α-球蛋白呈正相关,唾液酸,纤维蛋白原浓度与血清铁浓度呈负相关。死亡牛群的SAA浓度明显高于治愈的结果牛群。此外,从第一次测试到重新测试,治愈组的SAA浓度显着下降,但在废用组中显着增加。因此,SAA是炎症的敏感指标,也是日本黑牛的监测工具,并且其测量被认为在临床实践中有用。
公众号