关键词: constant bias laboratory statistics method comparison proportional bias

Mesh : Animals Linear Models Laboratories Pathology, Clinical

来  源:   DOI:10.1111/vcp.13293

Abstract:
Current guidelines recommend using Bland-Altman plots (BA-plots), also called Difference plots, as part of method comparison evaluation in the veterinary clinical pathology laboratory. Analysis of differences can meaningfully augment linear regression techniques and allows fuller summarization of the performance of two methods relative to each other. This work summarizes the current literature on BA-plot composition and evaluation. Model data is used to demonstrate data evaluation approaches based on the observed differences, the combined inherent imprecision of the methods, and clinically relevant performance goals. Common limitations of the approaches, including points of frequent misinterpretation, are presented. BA-plot analysis can be part of an intentionally crafted method comparison study that provides analytically and clinically relevant data.
摘要:
当前指南建议使用Bland-Altman地块(BA地块),也称为差异图,作为兽医临床病理实验室方法比较评价的一部分。差异分析可以有意义地增强线性回归技术,并允许更全面地总结两种方法相对于彼此的性能。这项工作总结了当前有关BA情节组成和评估的文献。模型数据用于展示基于观察到的差异的数据评估方法,这些方法的综合固有不精确性,和临床相关的性能目标。这些方法的共同局限性,包括经常误解的观点,被呈现。BA图分析可以是有意制作的方法比较研究的一部分,该方法提供分析和临床相关数据。
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