PDF(Pubmed)
Abstract：
The annual increase in the number of camels entails a parallel increase in the incidence of trichophytosis, which poses a great threat to the health and life of both this species of animals and other organisms that contact and surround them.
The aim of the study was to develop and establish the quality of vaccines inactivated by ultrasonic exposure for the prevention and treatment of trichophytosis in camels, and to compare them with chemically deactivated vaccines.
The peculiarity of the technology of production of these vaccines was the use of an innovative method of inactivation of fungal strains by ultrasonic waves, which allowed to achieve high positive results in theory, and was subsequently confirmed in practice by immunizing sick and healthy animals. The first tests of the obtained vaccines were conducted in laboratory conditions on experimental rabbits.
The results of prophylactic and therapeutic vaccinations were one hundred percent positive, which made it possible to conduct further tests directly on camels of industrial farms, the expected result of which was also positively confirmed at the end of the research.
As a result of this experiment, the effectiveness, stability, and safety of the manufactured vaccines were established, which made it possible to approve the regulatory and technical documentation and patent them as an innovative and effective development for the prevention and treatment of camel trichophytosis, which will reduce the growth of infection and further overcome the mass spread of the disease both among camels and among the surrounding organisms to which it is transmitted.
The aim of the study was to develop and establish the quality of vaccines inactivated by ultrasonic exposure for the prevention and treatment of trichophytosis in camels, and to compare them with chemically deactivated vaccines.
The peculiarity of the technology of production of these vaccines was the use of an innovative method of inactivation of fungal strains by ultrasonic waves, which allowed to achieve high positive results in theory, and was subsequently confirmed in practice by immunizing sick and healthy animals. The first tests of the obtained vaccines were conducted in laboratory conditions on experimental rabbits.
The results of prophylactic and therapeutic vaccinations were one hundred percent positive, which made it possible to conduct further tests directly on camels of industrial farms, the expected result of which was also positively confirmed at the end of the research.
As a result of this experiment, the effectiveness, stability, and safety of the manufactured vaccines were established, which made it possible to approve the regulatory and technical documentation and patent them as an innovative and effective development for the prevention and treatment of camel trichophytosis, which will reduce the growth of infection and further overcome the mass spread of the disease both among camels and among the surrounding organisms to which it is transmitted.
摘要：
■骆驼数量的每年增加导致毛癣菌的发病率同时增加，这对这种动物和其他接触和围绕它们的生物的健康和生命构成了巨大威胁。
■这项研究的目的是开发和建立通过超声波暴露灭活的疫苗的质量，以预防和治疗骆驼的毛癣菌病，并将它们与化学灭活的疫苗进行比较。
■生产这些疫苗的技术的特殊性是使用一种通过超声波灭活真菌菌株的创新方法，这使得理论上取得了很高的积极成果，并随后在实践中通过对患病和健康的动物进行免疫接种得到证实。在实验室条件下对实验兔进行了获得的疫苗的首次测试。
■预防性和治疗性疫苗接种的结果是百分之百阳性，这使得直接在工业农场的骆驼上进行进一步的测试成为可能，其预期结果在研究结束时也得到了肯定.
■作为这个实验的结果，的有效性,稳定性,并建立了生产疫苗的安全性，这使得有可能批准监管和技术文件，并将其专利作为预防和治疗骆驼毛癣病的创新和有效发展，这将减少感染的增长，并进一步克服疾病在骆驼和周围生物之间的大规模传播。
■这项研究的目的是开发和建立通过超声波暴露灭活的疫苗的质量，以预防和治疗骆驼的毛癣菌病，并将它们与化学灭活的疫苗进行比较。
■生产这些疫苗的技术的特殊性是使用一种通过超声波灭活真菌菌株的创新方法，这使得理论上取得了很高的积极成果，并随后在实践中通过对患病和健康的动物进行免疫接种得到证实。在实验室条件下对实验兔进行了获得的疫苗的首次测试。
■预防性和治疗性疫苗接种的结果是百分之百阳性，这使得直接在工业农场的骆驼上进行进一步的测试成为可能，其预期结果在研究结束时也得到了肯定.
■作为这个实验的结果，的有效性,稳定性,并建立了生产疫苗的安全性，这使得有可能批准监管和技术文件，并将其专利作为预防和治疗骆驼毛癣病的创新和有效发展，这将减少感染的增长，并进一步克服疾病在骆驼和周围生物之间的大规模传播。
