关键词: Case reports diagnosis. male breast cancer prognosis review risk factors

Mesh : Humans Male Female Breast Neoplasms, Male / diagnosis therapy epidemiology Retrospective Studies Prospective Studies Breast Neoplasms / metabolism Prognosis Receptors, Estrogen / metabolism

来  源:   DOI:10.2174/1871520623666230821124008

Abstract:
Male breast cancer (MBC) accounts for 0.5%-1% of all breast cancers diagnosed worldwide. However, its biological characteristics can be distinguished from that of female breast cancer (FBC).
The diagnostic and treatment approaches for MBC are mainly similar to that of FBC due to the lack of male breast cancer-related studies, clinical trials, and literature. An increasing number of retrospective and prospective studies have been conducted to clarify the individualized care for MBC. Herein, we report three cases of advanced MBC to describe the diagnostic approaches, treatment process, and survival prognosis.
MBC patients had older age, later stage at first diagnosis, higher expression of hormone receptors, and poor prognosis. A literature review was conducted to determine the incidence, risk factors, disease features, diagnosis, treatment, survival, and management of MBC.
摘要:
背景:男性乳腺癌(MBC)占全球诊断的所有乳腺癌的0.5%-1%。然而,其生物学特性可与女性乳腺癌(FBC)相鉴别。
方法:由于缺乏男性乳腺癌相关研究,MBC的诊断和治疗方法主要与FBC相似。临床试验,和文学。已经进行了越来越多的回顾性和前瞻性研究,以阐明MBC的个性化护理。在这里,我们报告了三例晚期MBC来描述诊断方法,处理过程,和生存预后。
结论:MBC患者年龄较大,在最初诊断的后期,激素受体的高表达,预后不良。进行了文献综述以确定发生率,危险因素,疾病特征,诊断,治疗,生存,和MBC的管理。
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