UNASSIGNED: The study was conducted in a private teaching dental institute and hospital setting. Out of 615 incisional biopsies received in the department of oral pathology, between June 2019 and April 2021, n = 22 samples were immune-mediated vesiculobullous lesions confirmed by clinical and histopathological diagnosis after eliminating lesions of viral origin. Patient details including age, gender, site, duration, and systemic illness were collected from the digital information archiving software and analyzed by appropriate statistics using SPSS software.
UNASSIGNED: Based on the results, 95.5% of the patients had histopathological features of intraepithelial clefting and only 4.5% of them showed subepithelial clefting. Female predilection was 6.3:1. The most common site of involvement was nonkeratinized mucosa (36.36%) and 59.09% of the patients presented with systemic illness.
UNASSIGNED: The study shows most of the features of pemphigus is consistent in gingiva and other parts of oral mucosa. The dental practitioners should be aware of the various oral manifestations of such lesions to ensure accurate diagnosis and adequate treatment.
■这项研究是在一家私立牙科教学机构和医院环境中进行的。在口腔病理科接受的615例切开活检中,在2019年6月至2021年4月期间,n=22个样本为免疫介导的囊泡囊性病变,在消除病毒来源的病变后,经临床和组织病理学诊断证实.患者详细信息,包括年龄,性别,site,持续时间,从数字信息存档软件中收集系统性疾病,并使用SPSS软件进行适当的统计学分析.
■根据结果,95.5%的患者具有上皮内裂开的组织病理学特征,只有4.5%的患者表现为上皮下裂开。女性好发指数为6.3:1。最常见的受累部位是非角化粘膜(36.36%),59.09%的患者出现全身性疾病。
■研究表明,天疱疮的大多数特征在牙龈和口腔粘膜的其他部位是一致的。牙科医生应了解此类病变的各种口腔表现,以确保准确诊断和适当治疗。