PDF(Pubmed)
Abstract：
Introduction: Different therapies have been applied to keloids and hypertrophic scars. Intense pulsed light (IPL) has recently been used but the evidence is limited. This study was to evaluate the effectiveness and safety of IPL as monotherapy for keloids and hypertrophic scars. Methods: This was a before-and-after interventional study on 16 patients with 50 scars who underwent IPL. Seven scars receive one IPL session, seven received two sessions, and 36 received three sessions. Outcomes were evaluated by the Vancouver Scar Scale (VSS), Patient and Observer Scar Assessment Scale (POSAS), scar ultrasound, colorimeter for pigmentation and erythema, and side effects. Results: After the treatment, most outcomes significantly improved except that the pigmentation of the scars did not change. Scar thickness significantly reduced by nearly 10% after the first IPL session, 15% after the second session, and>20% after the third session. All side effects were mild with crust (33.3-46%), blisters (8.3-40%), and hyperpigmentation around the scar (0-14%); the pain was moderate as assessed by the patients. Conclusion: IPL is a safe and effective treatment for keloids and hypertrophic scars. More studies are required to confirm our results.
摘要：
简介：不同的疗法已应用于瘢痕疙瘩和肥厚性瘢痕。最近使用了强脉冲光（IPL），但证据有限。这项研究旨在评估IPL作为瘢痕疙瘩和肥厚性瘢痕的单一疗法的有效性和安全性。方法：这是一项对16例50例接受IPL的疤痕患者进行的前后介入研究。七个伤疤收到一个IPL会话，七个人接受了两次会议，36人参加了三场会议。结果由温哥华疤痕量表(VSS)评估，患者和观察者疤痕评估量表(POSAS)瘢痕超声,色素沉着和红斑比色计，和副作用。结果:经过治疗,除了疤痕的色素沉着没有改变外,大多数结局都显著改善.第一次IPL会议后，疤痕厚度显着减少了近10％，第二次会议后15%，第三次会议后>20%。所有副作用都是温和的结皮（33.3-46％），水泡（8.3-40%），和瘢痕周围的色素沉着过度（0-14％）；根据患者的评估，疼痛是中度的。结论：IPL是治疗瘢痕疙瘩和增生性瘢痕的一种安全有效的方法。需要更多的研究来证实我们的结果。
