Abstract:
Multimodal treatment, including assisted reproductive technology, is necessary in young patients with advanced borderline ovarian tumors. However, the details of long-term follow-up cases have not been reported. In this report, a 19-year-old patient presented with a stage IIIC serous borderline tumor. The patient underwent five fertility-sparing surgeries. The tumor did not respond to any of the three lines of chemotherapy administered. Serological and radiological responses were observed following hormonal treatment with leuprorelin, followed by a fourth surgery. Before the planned fifth surgery for complete resection of both adnexa, cryopreservation of the fertilized eggs was performed. At age 36, when the disease-free interval exceeded the previous one, we proposed embryo transfer; however, she declined fertility treatment. The patient had developed rheumatoid arthritis and childbirth not a priority. The patient had lived without any evidence of disease for 7 years following the last surgery and 20 years after the initial visit.
摘要:
多模式治疗,包括辅助生殖技术,对于患有晚期交界性卵巢肿瘤的年轻患者是必要的。然而,长期随访病例的细节尚未报告。在这份报告中,1例19岁患者出现IIIC期浆液性交界性肿瘤.患者接受了五次保留生育能力的手术。肿瘤对所施用的三种化疗线中的任何一种均无反应。用亮丙瑞林激素治疗后观察到血清学和放射学反应,接着是第四次手术.在计划进行第五次手术以完全切除两个附件之前,对受精卵进行冷冻保存。36岁时,当无病间隔超过前一个时,我们提出了胚胎移植,然而,她拒绝生育治疗。患者患有类风湿性关节炎,分娩不是优先事项。患者在最后一次手术后7年和初次就诊后20年没有任何疾病证据。