Abstract：
BACKGROUND: The aim of this study was to examine if choroidal vascularity index (CVI) is different in eyes with unilateral vitreomacular traction (VMT) from their healthy fellow eyes; and whether different treatments affect the CVI.
METHODS: The baseline and 8-week post treatment CVIs of 56 unilateral VMT patients that underwent spontaneous resolution (n = 30), vitreoretinal surgery (n = 16) or pneumatic vitreolysis (n = 10) were compared with fellow eyes using paired samples t-test. Partial correlation analyses correcting age and gender was used for calculations between treatment groups. P values < 0.05 were considered statistically significant.
RESULTS: The mean baseline CVI for VMT and control eyes had no statistically significant difference (p = 0.81, r= -0.38). The post traction release follow-up CVI of VMT eyes and contralateral eyes had no significant difference (p = 0.12, r = 0.49). In spontaneous resolution group, vitreoretinal surgery group and pneumatic vitreolysis group the baseline and follow up CVIs of VMT eyes were statistically similar (p = 0.72, p = 0.32 and p = 0.79 respectively).Spontaneous detachment patients\' CVIs showed a 0.57±5.81% increase, vitreoretinal surgery group had a reduction of 1.098±4.76%, and the pneumatic vitreolysis patients showed a CVI reduction of 0.307±4.24%. However, none of these changes was found to be statistically significant when compared between the groups (p = 0.21, r = 0.02).
CONCLUSIONS: Previous studies have argued that vitreomacular traction might have a role on the choroidal changes seen in the vitreoretinal interface disorders. This study has shown that VMT alone does not cause any significant changes in choroidal vascular index pre or post traction release.
METHODS: The baseline and 8-week post treatment CVIs of 56 unilateral VMT patients that underwent spontaneous resolution (n = 30), vitreoretinal surgery (n = 16) or pneumatic vitreolysis (n = 10) were compared with fellow eyes using paired samples t-test. Partial correlation analyses correcting age and gender was used for calculations between treatment groups. P values < 0.05 were considered statistically significant.
RESULTS: The mean baseline CVI for VMT and control eyes had no statistically significant difference (p = 0.81, r= -0.38). The post traction release follow-up CVI of VMT eyes and contralateral eyes had no significant difference (p = 0.12, r = 0.49). In spontaneous resolution group, vitreoretinal surgery group and pneumatic vitreolysis group the baseline and follow up CVIs of VMT eyes were statistically similar (p = 0.72, p = 0.32 and p = 0.79 respectively).Spontaneous detachment patients\' CVIs showed a 0.57±5.81% increase, vitreoretinal surgery group had a reduction of 1.098±4.76%, and the pneumatic vitreolysis patients showed a CVI reduction of 0.307±4.24%. However, none of these changes was found to be statistically significant when compared between the groups (p = 0.21, r = 0.02).
CONCLUSIONS: Previous studies have argued that vitreomacular traction might have a role on the choroidal changes seen in the vitreoretinal interface disorders. This study has shown that VMT alone does not cause any significant changes in choroidal vascular index pre or post traction release.
摘要：
背景：这项研究的目的是检查单侧玻璃体黄斑牵引（VMT）的脉络膜血管指数（CVI）是否与健康的眼睛不同；以及不同的治疗方法是否会影响CVI。
方法：56例接受自发消退的单侧VMT患者（n=30）的基线和治疗后8周的CVI，使用配对样本t检验将玻璃体视网膜手术（n=16）或充气玻璃体溶解术（n=10）与其他眼进行比较。校正年龄和性别的偏相关分析用于治疗组之间的计算。P值<0.05被认为具有统计学意义。
结果：VMT和对照眼的平均基线CVI无统计学差异（p=0.81，r=-0.38）。牵引松解术后随访时VMT眼与对侧眼的CVI差异无统计学意义(p=0.12,r=0.49)。在自发解决组中，玻璃体视网膜手术组和充气玻璃体溶解组VMT眼的基线和随访CVIs有统计学相似(分别为p=0.72、p=0.32和p=0.79)。自发性脱离患者的CVIs增加了0.57±5.81%，玻璃体视网膜手术组减少1.098±4.76%,充气玻璃体溶解患者CVI降低0.307±4.24%。然而,组间比较，这些变化均无统计学意义（p=0.21，r=0.02）。
结论：先前的研究认为玻璃体黄斑牵引可能对玻璃体视网膜界面疾病中的脉络膜变化有一定作用。这项研究表明，单独的VMT不会在牵引释放前或后引起脉络膜血管指数的任何显着变化。
方法：56例接受自发消退的单侧VMT患者（n=30）的基线和治疗后8周的CVI，使用配对样本t检验将玻璃体视网膜手术（n=16）或充气玻璃体溶解术（n=10）与其他眼进行比较。校正年龄和性别的偏相关分析用于治疗组之间的计算。P值<0.05被认为具有统计学意义。
结果：VMT和对照眼的平均基线CVI无统计学差异（p=0.81，r=-0.38）。牵引松解术后随访时VMT眼与对侧眼的CVI差异无统计学意义(p=0.12,r=0.49)。在自发解决组中，玻璃体视网膜手术组和充气玻璃体溶解组VMT眼的基线和随访CVIs有统计学相似(分别为p=0.72、p=0.32和p=0.79)。自发性脱离患者的CVIs增加了0.57±5.81%，玻璃体视网膜手术组减少1.098±4.76%,充气玻璃体溶解患者CVI降低0.307±4.24%。然而,组间比较，这些变化均无统计学意义（p=0.21，r=0.02）。
结论：先前的研究认为玻璃体黄斑牵引可能对玻璃体视网膜界面疾病中的脉络膜变化有一定作用。这项研究表明，单独的VMT不会在牵引释放前或后引起脉络膜血管指数的任何显着变化。
