Abstract：
To evaluate and compare mini-laparotomy (MLPT) with laparoscopic (LPS) myomectomy perioperative and reproductive outcomes.
We systematically searched for related articles in the MEDLINE, Embase, Web of Science and the Cochrane library databases. Nine studies (4 randomized, 3 retrospective, 1 prospective and 1 case-control study) which involved 1723 patients met the inclusion criteria and were considered eligible for inclusion.
Demographic characteristics were similar between the two groups. LPS was associated with shorter hospital stay (p = 0.04), lower blood loss (p < 0.00001), shorter duration of median ileus (p < 0.00001) and fewer episodes of postoperative fever (p = 0.04). None of the reproductive factors examined (pregnancy rate, preterm delivery, vaginal delivery and delivery with caesarean section) in women diagnosed with unexplained infertility and/or symptomatic leiomyomas reached statistical significance although the results represent a small size effect.
Our analysis demonstrated that LPS seems to be an alternative, safe and reliable surgical procedure for uterine leiomyoma treatment and in everyday practice seems to offer improved outcomes-regarding at least the perioperative period-over MLPT.
We systematically searched for related articles in the MEDLINE, Embase, Web of Science and the Cochrane library databases. Nine studies (4 randomized, 3 retrospective, 1 prospective and 1 case-control study) which involved 1723 patients met the inclusion criteria and were considered eligible for inclusion.
Demographic characteristics were similar between the two groups. LPS was associated with shorter hospital stay (p = 0.04), lower blood loss (p < 0.00001), shorter duration of median ileus (p < 0.00001) and fewer episodes of postoperative fever (p = 0.04). None of the reproductive factors examined (pregnancy rate, preterm delivery, vaginal delivery and delivery with caesarean section) in women diagnosed with unexplained infertility and/or symptomatic leiomyomas reached statistical significance although the results represent a small size effect.
Our analysis demonstrated that LPS seems to be an alternative, safe and reliable surgical procedure for uterine leiomyoma treatment and in everyday practice seems to offer improved outcomes-regarding at least the perioperative period-over MLPT.
摘要：
目的：评估和比较小开腹手术（MLPT）与腹腔镜（LPS）子宫肌瘤切除术的围手术期和生殖结局。
方法：我们系统地搜索了MEDLINE中的相关文章，Embase,WebofScience和Cochrane图书馆数据库。9项研究（4项随机，3回顾性，1项前瞻性和1项病例对照研究），涉及1723例患者，符合纳入标准，被认为符合纳入标准。
结果：两组人口统计学特征相似。LPS与住院时间较短有关（p=0.04），降低失血量（p<0.00001），中位肠梗阻持续时间较短(p<0.00001),术后发热发生率较低(p=0.04).没有检查的生殖因素(怀孕率，早产,经诊断患有无法解释的不孕症和/或有症状的平滑肌瘤的妇女的阴道分娩和剖腹产）达到了统计学意义，尽管结果代表了小尺寸效应。
结论：我们的分析表明LPS似乎是一种替代方法，安全可靠的手术治疗子宫平滑肌瘤,在日常实践中,在MLPT治疗中,至少在围手术期,似乎提供了改善的结局.
方法：我们系统地搜索了MEDLINE中的相关文章，Embase,WebofScience和Cochrane图书馆数据库。9项研究（4项随机，3回顾性，1项前瞻性和1项病例对照研究），涉及1723例患者，符合纳入标准，被认为符合纳入标准。
结果：两组人口统计学特征相似。LPS与住院时间较短有关（p=0.04），降低失血量（p<0.00001），中位肠梗阻持续时间较短(p<0.00001),术后发热发生率较低(p=0.04).没有检查的生殖因素(怀孕率，早产,经诊断患有无法解释的不孕症和/或有症状的平滑肌瘤的妇女的阴道分娩和剖腹产）达到了统计学意义，尽管结果代表了小尺寸效应。
结论：我们的分析表明LPS似乎是一种替代方法，安全可靠的手术治疗子宫平滑肌瘤,在日常实践中,在MLPT治疗中,至少在围手术期,似乎提供了改善的结局.
