PDF(Pubmed)
Abstract：
UNASSIGNED: Following debridement, the skin and mucous membranes around the wound must be disinfected with broad-spectrum disinfectants like Iodophor, 75 % ethanol, chlorhexidine, and bromogeramine. Despite the fact that it is rarely reported, skin allergy to disinfectants is extremely detrimental to wound recovery after debridement.
METHODS: In this study, a 29-year-old man with no previous allergic history developed delayed contact dermatitis after being exposed to multiple disinfectants, including iodophor, 75 % ethanol, and Erythromycin ointment. Given the possibility of the patient\'s allergic constitution, skin patch tests were repeated to confirm the allergic disinfectants. To avoid the allergy, the wound was simply rinsed with 0.9 % sodium chloride solution and Cefdinir (0.1 g, tid) was taken orally, while all local disinfectants were discontinued. The wound healing process was gradually accelerated, and allergic symptoms were alleviated. Furthermore, our findings revealed that the frequency and immunosuppressive function of Tregs were significantly lower in patients than in healthy controls (P < 0.05).
UNASSIGNED: By minimizing allergic reactions and providing appropriate wound care, the use of 0.9 % sodium chloride solution with oral antibiotics could expedite the healing process. This enabled the wound to close faster and reduces the risk of complications.
CONCLUSIONS: The use of 0.9 % sodium chloride solution for wound irrigation, combined with oral administration of antibiotics, could be modified to mitigate further allergic reactions and enhance the recovery process following debridement. However, individual patient characteristics and medical history should also be taken into consideration when making these alterations.
METHODS: In this study, a 29-year-old man with no previous allergic history developed delayed contact dermatitis after being exposed to multiple disinfectants, including iodophor, 75 % ethanol, and Erythromycin ointment. Given the possibility of the patient\'s allergic constitution, skin patch tests were repeated to confirm the allergic disinfectants. To avoid the allergy, the wound was simply rinsed with 0.9 % sodium chloride solution and Cefdinir (0.1 g, tid) was taken orally, while all local disinfectants were discontinued. The wound healing process was gradually accelerated, and allergic symptoms were alleviated. Furthermore, our findings revealed that the frequency and immunosuppressive function of Tregs were significantly lower in patients than in healthy controls (P < 0.05).
UNASSIGNED: By minimizing allergic reactions and providing appropriate wound care, the use of 0.9 % sodium chloride solution with oral antibiotics could expedite the healing process. This enabled the wound to close faster and reduces the risk of complications.
CONCLUSIONS: The use of 0.9 % sodium chloride solution for wound irrigation, combined with oral administration of antibiotics, could be modified to mitigate further allergic reactions and enhance the recovery process following debridement. However, individual patient characteristics and medical history should also be taken into consideration when making these alterations.
摘要：
■清创术后，伤口周围的皮肤和粘膜必须用广谱消毒剂消毒，75%乙醇，氯己定,和溴洁尔胺.尽管它很少被报道，对消毒剂的皮肤过敏对清创后的伤口恢复极为不利。
方法：在本研究中，一名没有过敏史的29岁男子在接触多种消毒剂后出现迟发性接触性皮炎，包括碘伏,75%乙醇，和红霉素软膏.考虑到患者过敏体质的可能性，重复皮肤贴片测试以确认过敏性消毒剂。为了避免过敏，用0.9%氯化钠溶液和头孢地尼(0.1克，tid)是口服的，而所有本地消毒剂均已停用。伤口愈合过程逐渐加快，过敏症状缓解。此外，我们的发现显示，患者Tregs的频率和免疫抑制功能明显低于健康对照组（P<0.05）。
■通过减少过敏反应并提供适当的伤口护理，使用0.9%氯化钠溶液和口服抗生素可以加速愈合过程.这使伤口能够更快地闭合并降低并发症的风险。
结论：使用0.9%氯化钠溶液进行伤口冲洗，结合口服抗生素，可以修改以减轻进一步的过敏反应并增强清创后的恢复过程。然而,进行这些改变时,还应考虑患者的个体特征和病史.
方法：在本研究中，一名没有过敏史的29岁男子在接触多种消毒剂后出现迟发性接触性皮炎，包括碘伏,75%乙醇，和红霉素软膏.考虑到患者过敏体质的可能性，重复皮肤贴片测试以确认过敏性消毒剂。为了避免过敏，用0.9%氯化钠溶液和头孢地尼(0.1克，tid)是口服的，而所有本地消毒剂均已停用。伤口愈合过程逐渐加快，过敏症状缓解。此外，我们的发现显示，患者Tregs的频率和免疫抑制功能明显低于健康对照组（P<0.05）。
■通过减少过敏反应并提供适当的伤口护理，使用0.9%氯化钠溶液和口服抗生素可以加速愈合过程.这使伤口能够更快地闭合并降低并发症的风险。
结论：使用0.9%氯化钠溶液进行伤口冲洗，结合口服抗生素，可以修改以减轻进一步的过敏反应并增强清创后的恢复过程。然而,进行这些改变时,还应考虑患者的个体特征和病史.
