METHODS: Data of patients undergoing D2-OG or RG for gastric cancer were retrieved from the international IMIGASTRIC prospective database and compared.
RESULTS: A total of 1469 patients were selected for inclusion in the study. After 1:1 propensity score matching, a total of 580 patients were matched and included in the final analysis, 290 in each group, RG vs OG. RG had longer operation time (210 vs 330 min, p < 0.0001), reduced intraoperative blood loss (155 vs 119.7 ml, p < 0.0001), time to liquid diet (4.4 vs 3 days, p < 0.0001) and to peristalsis (2.4 vs 2 days, p < 0.0001), and length of postoperative stay (11 vs 8 days, p < 0.0001). Morbidity rate was higher in OG (24.1% vs 16.2%, p = 0.017).
CONCLUSIONS: RG significantly expedites recovery and reduces the risk of complications compared to OG. However, long-term survival is similar.
方法:从国际IMIGASTRIC前瞻性数据库中检索并比较接受D2-OG或RG胃癌患者的数据。
结果:共选择1469例患者纳入研究。1:1倾向评分匹配后,共580例患者进行匹配,并纳入最终分析,每组290人,RGvsOG。RG的手术时间更长(210对330分钟,p<0.0001),术中失血减少(155vs119.7ml,p<0.0001),流质饮食时间(4.4vs3天,p<0.0001)和蠕动(2.4vs2天,p<0.0001),和术后住院时间(11vs8天,p<0.0001)。OG发病率较高(24.1%vs16.2%,p=0.017)。
结论:与OG相比,RG可显著加速康复并降低并发症的风险。然而,长期生存是相似的。