PDF(Pubmed)
Abstract：
Echinococcosis is primarily a disease of developing nations with poor medical infrastructure, where cohabitation with domesticated animals is common. These conditions, in conjunction with the inherent chronicity of the disease, lead to low rates of diagnosis and high morbidity. Robust surveillance is not readily available in communities with the highest disease burden.WHO classifications assist in diagnostic and treatment endeavours especially in countries where this disease is not commonly encountered. However, the understanding of the pathophysiology of echinococcosis and optimal treatment are still lacking in certain patient populations.We present the case of a female from Central Asia with an isolated pulmonary hydatid cyst. She was diagnosed several months after she had an uncomplicated pregnancy and gave birth to a healthy baby girl. Due to a delay in surgical intervention, our patient received a prolonged course of treatment which resulted in a significant reduction in the size of the cyst. Given her improvement, we questioned the current guidelines set by the WHO regarding surgical resection of pulmonary hydatid cysts, compared with an extended course with albendazole in patients with an unusual and protracted course of the disease. Furthermore, we discuss the possible role of pregnancy in exacerbating symptoms of underlying pulmonary hydatid disease.
摘要：
棘球蚴病主要是医疗基础设施差的发展中国家的一种疾病，与家养动物同居的地方很常见。这些条件,结合疾病固有的慢性，导致低诊断率和高发病率。在疾病负担最高的社区中，强有力的监测并不容易获得。世卫组织的分类有助于诊断和治疗工作，特别是在这种疾病不常见的国家。然而,在某些患者人群中，对包虫病的病理生理学和最佳治疗仍缺乏了解。我们介绍了一名来自中亚的女性，患有孤立的肺包虫囊肿。在她没有复杂的怀孕并生下一个健康的女婴几个月后，她被诊断出。由于手术干预的延迟，我们的患者接受了延长疗程的治疗，导致囊肿的大小显著减小。鉴于她的进步，我们质疑世界卫生组织关于肺包虫囊肿手术切除的现行指南，与阿苯达唑延长病程的患者相比，该疾病的病程异常和延长。此外，我们讨论了妊娠在加重潜在肺包虫病症状中的可能作用。
