Abstract：
Rhabdomyosarcoma is the most common soft-tissue neoplasm in the pediatric population. The survival of children with rhabdomyosarcoma has only marginally improved over the past 25 years and remains poor for those with metastatic disease. A significant challenge to advances in treatment of rhabdomyosarcoma is the relative rarity of this disease, necessitating years to complete clinical trials. Progress can be accelerated by international cooperation and sharing national experiences. This necessitates agreement on a common language to describe patient cohorts and consensus standards to guide diagnosis, treatment, and response assessment. These goals formed the premise for creating the INternational Soft Tissue saRcoma ConsorTium (INSTRuCT) in 2017. Multidisciplinary members of this consortium have since developed international consensus statements on the diagnosis, treatment, and management of pediatric soft-tissue sarcomas. Herein, members of the INSTRuCT Diagnostic Imaging Working Group present international consensus recommendations for imaging of patients with rhabdomyosarcoma at diagnosis, at staging, and during and after completion of therapy. The intent is to promote a standardized imaging approach to pediatric patients with this malignancy to create more-reliable comparisons of results of clinical trials internationally, thereby accelerating progress in managing rhabdomyosarcoma and improving survival.
摘要：
横纹肌肉瘤是儿科人群中最常见的软组织肿瘤。在过去的25年中，患有横纹肌肉瘤的儿童的生存率仅略有改善，对于患有转移性疾病的儿童来说仍然很差。横纹肌肉瘤治疗进展的一个重大挑战是这种疾病的相对罕见，完成临床试验需要数年时间。可以通过国际合作和分享国家经验来加速进展。这需要就描述患者队列的共同语言和指导诊断的共识标准达成一致。治疗,和反应评估。这些目标为在2017年创建国际软组织肉瘤（INSTRuCT）奠定了前提。此后，该财团的多学科成员就该诊断制定了国际共识声明，治疗,和小儿软组织肉瘤的管理。在这里，INSTRuCT诊断成像工作组成员就横纹肌肉瘤患者的诊断成像提出了国际共识建议,在分期时，治疗期间和结束后。目的是为患有这种恶性肿瘤的儿科患者推广标准化的成像方法，以创建更可靠的国际临床试验结果比较，从而加速治疗横纹肌肉瘤和提高生存率的进展。
