PDF(Pubmed)
Abstract：
We report the first known case of an adrenal teratoma containing a Wilms tumor component, in a 12-month-old girl with Trisomy 21. Despite adrenal teratomas being relatively uncommon, this particular instance raises interesting questions regarding the tumor origin, given the coexistence of both a teratoma and a Wilms tumor. Two main theories of development have been hypothesized, one of which suggests that the Wilms tumor may develop from a primary teratoma and the other proposing that the teratoma could originate from a primary Wilms tumor. Our case study leans toward the former, as the majority of the tumor displayed characteristics of a typical mature teratoma, with the Wilms component discovered as an incidental finding. Successful surgical intervention led to the gross total resection of the tumor. Twelve months post-resection, the patient remains free of recurrence. This report contributes to our understanding of these rare tumor types and underlines the importance of identifying the primary tumor to ensure appropriate management and treatment.
摘要：
我们报告了第一例已知的肾上腺畸胎瘤，其中含有Wilms肿瘤成分，一个12个月大的21三体女孩.尽管肾上腺畸胎瘤相对不常见，这个特殊的例子引发了关于肿瘤起源的有趣问题，考虑到畸胎瘤和Wilms肿瘤的共存。提出了两种主要的发展理论，其中一个提示Wilms肿瘤可能由原发性畸胎瘤发展而另一个提示畸胎瘤可能源自原发性Wilms肿瘤.我们的案例研究倾向于前者，由于大多数肿瘤表现出典型的成熟畸胎瘤的特征，Wilms组件是偶然发现的。成功的手术干预导致肿瘤的完全切除。切除后12个月,患者仍无复发。本报告有助于我们了解这些罕见的肿瘤类型，并强调确定原发肿瘤以确保适当的管理和治疗的重要性。
