Abstract：
Limited by spatial and temporal resolution, traditional optical microscopy cannot image the delicate ultra-structure organelles and sub-organelles. The emergence of super-resolution microscopy makes it possible. In this review, we focus on mitochondria. We summarize the process of mitochondrial dynamics, the primary proteins that regulate mitochondrial morphology, the diseases related to mitochondrial dynamics. The purpose is to apply super-resolution microscopy developed during recent years to the mitochondrial research. By providing the right research tools, we will help to promote the application of this technique to the in-depth elucidation of the pathogenesis of diseases related to mitochondrial dynamics, assistdiagnosis and develop the therapeutic treatment.
摘要：
受空间和时间分辨率的限制，传统的光学显微镜无法对精致的超微结构细胞器和亚细胞器进行成像。超分辨率显微镜的出现使之成为可能。在这次审查中,我们专注于线粒体。我们总结了线粒体动力学的过程，调节线粒体形态的主要蛋白质，与线粒体动力学有关的疾病。-目的是将近年来开发的超分辨率显微镜应用于线粒体研究。通过提供正确的研究工具，我们将有助于促进该技术的应用，深入阐明与线粒体动力学相关的疾病的发病机理，辅助诊断和发展治疗。
