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Abstract：
UNASSIGNED: A number of articles report the association of polypoidal lesions and choroidal nevi; however, the relationship between choroidal nevi and pachychoroidal disorders has not been studied.
UNASSIGNED: To study the prevalence of choroidal nevi in central serous chorioretinopathy (CSCR) patients and to elucidate potential differences in the clinical characteristics of CSCR in patients with and without choroidal nevi.
UNASSIGNED: Case-control study.
UNASSIGNED: This study included a retrospective analysis of medical records and multimodal imaging data of CSCR patients and a prospective evaluation of the prevalence of the choroidal nevi in age- and sex-matched healthy controls. All participants received comprehensive ophthalmic examination and multimodal imaging including infrared scanning laser ophthalmoscopy in dark-field mode to detect choroidal nevi in the central 40° × 60° region.
UNASSIGNED: A total of 199 CSCR patients (160 males and 39 females, 47.9 ± 9.4 years) and 184 age-matched healthy individuals (139 males and 45 females, 44.8 ± 12.5 years) were included. Choroidal nevi were detected in 24 (12.1%) CSCR patients and 10 (5.4%) healthy controls (p = 0.01). CSCR patients with choroidal nevi had statistically significantly higher subfoveal choroidal thickness, lower best-corrected visual acuity, and lower central retinal thickness (p < 0.05) than CSCR patients without choroidal nevi. The odds ratio for the presence of chronic CSCR in patients with choroidal nevi was 27.0 (95% CI: 3.1-231.9, p = 0.003).
UNASSIGNED: The prevalence of choroidal nevi among patients with CSCR is higher than in age- and sex-matched healthy population. Choroidal nevi may be associated with chronic CSCR.
UNASSIGNED: To study the prevalence of choroidal nevi in central serous chorioretinopathy (CSCR) patients and to elucidate potential differences in the clinical characteristics of CSCR in patients with and without choroidal nevi.
UNASSIGNED: Case-control study.
UNASSIGNED: This study included a retrospective analysis of medical records and multimodal imaging data of CSCR patients and a prospective evaluation of the prevalence of the choroidal nevi in age- and sex-matched healthy controls. All participants received comprehensive ophthalmic examination and multimodal imaging including infrared scanning laser ophthalmoscopy in dark-field mode to detect choroidal nevi in the central 40° × 60° region.
UNASSIGNED: A total of 199 CSCR patients (160 males and 39 females, 47.9 ± 9.4 years) and 184 age-matched healthy individuals (139 males and 45 females, 44.8 ± 12.5 years) were included. Choroidal nevi were detected in 24 (12.1%) CSCR patients and 10 (5.4%) healthy controls (p = 0.01). CSCR patients with choroidal nevi had statistically significantly higher subfoveal choroidal thickness, lower best-corrected visual acuity, and lower central retinal thickness (p < 0.05) than CSCR patients without choroidal nevi. The odds ratio for the presence of chronic CSCR in patients with choroidal nevi was 27.0 (95% CI: 3.1-231.9, p = 0.003).
UNASSIGNED: The prevalence of choroidal nevi among patients with CSCR is higher than in age- and sex-matched healthy population. Choroidal nevi may be associated with chronic CSCR.
摘要：
■许多文章报道了息肉样病变和脉络膜痣的关联；然而，脉络膜痣与脉络膜病变之间的关系尚未研究。
■研究中心性浆液性脉络膜视网膜病变（CSCR）患者脉络膜痣的患病率，并阐明有无脉络膜痣患者CSCR临床特征的潜在差异。
■病例对照研究。
■本研究包括对CSCR患者的医疗记录和多模态影像学资料的回顾性分析，以及年龄和性别匹配的健康对照者脉络膜痣患病率的前瞻性评估。所有参与者都接受了全面的眼科检查和多模态成像，包括暗场模式的红外扫描激光检眼镜，以检测中央40°×60°区域的脉络膜痣。
■共有199名CSCR患者（男性160名，女性39名，47.9±9.4岁）和184名年龄匹配的健康个体（男性139名，女性45名，包括44.8±12.5年）。在24例（12.1%）CSCR患者和10例（5.4%）健康对照中检测到脉络膜痣（p=0.01）。CSCR脉络膜痣患者中央凹下脉络膜厚度明显增高,较低的最佳矫正视力，中央视网膜厚度低于无脉络膜痣的CSCR患者（p<0.05）。脉络膜痣患者存在慢性CSCR的比值比为27.0（95％CI：3.1-231.9，p=0.003）。
■CSCR患者脉络膜痣的患病率高于年龄和性别匹配的健康人群。脉络膜痣可能与慢性CSCR有关。
■研究中心性浆液性脉络膜视网膜病变（CSCR）患者脉络膜痣的患病率，并阐明有无脉络膜痣患者CSCR临床特征的潜在差异。
■病例对照研究。
■本研究包括对CSCR患者的医疗记录和多模态影像学资料的回顾性分析，以及年龄和性别匹配的健康对照者脉络膜痣患病率的前瞻性评估。所有参与者都接受了全面的眼科检查和多模态成像，包括暗场模式的红外扫描激光检眼镜，以检测中央40°×60°区域的脉络膜痣。
■共有199名CSCR患者（男性160名，女性39名，47.9±9.4岁）和184名年龄匹配的健康个体（男性139名，女性45名，包括44.8±12.5年）。在24例（12.1%）CSCR患者和10例（5.4%）健康对照中检测到脉络膜痣（p=0.01）。CSCR脉络膜痣患者中央凹下脉络膜厚度明显增高,较低的最佳矫正视力，中央视网膜厚度低于无脉络膜痣的CSCR患者（p<0.05）。脉络膜痣患者存在慢性CSCR的比值比为27.0（95％CI：3.1-231.9，p=0.003）。
■CSCR患者脉络膜痣的患病率高于年龄和性别匹配的健康人群。脉络膜痣可能与慢性CSCR有关。
