Abstract：
The Rh-D negative pregnancy is commonly associated with alloimmunization against D-antigen. It can be prevented by anti-D prophylaxis in pregnant patients with negative results on antibody screening. Hence, it is essential to exclude alloantibody-D in the presence of multiple alloantibodies. Anti-G antibody is formed after exposure to G antigen in neonate RBCs. Blood-group discrepancy was noted in reverse grouping, and antibody-screening results were positive in our case individual, a 28-year old Odiya Indian woman. We performed antibody identification on serum specimens from this patient, which revealed the pattern of anti-D + anti-C antibody specificity. Blood-group discrepancy was solved using rr (ce/ce)-phenotype pooled cells for reverse grouping. We identified anti-G antibodies by themselves without anti-D and anti-C after performing sequential adsorption of serum with r\'r\' (Ce/Ce) and R2R2 (DcE/DcE) group-O RBCs in the mother, who had rr phenotype and primigravida designation. After completing antibody screening at the first antenatal check-up, we recommended prophylactic anti-D for the mother in any future pregnancies she may have.
摘要：
Rh-D阴性妊娠通常与针对D抗原的同种免疫有关。在抗体筛查结果为阴性的妊娠患者中，可以通过抗D预防来预防。因此，在存在多种同种抗体的情况下,必须排除同种抗体-D.在新生儿RBC中暴露于G抗原后形成抗G抗体。在反向分组中发现血型差异，在我们的病例中，抗体筛查结果是阳性的，一个28岁的Odiya印度女人.我们对这名患者的血清标本进行了抗体鉴定，这揭示了抗D+抗C抗体特异性的模式。使用rr（ce/ce）-表型汇集的细胞进行反向分组，解决了血型差异。我们在母亲中使用r\'r\'（Ce/Ce）和R2R2（DcE/DcE）组-ORBC顺序吸附血清后，在没有抗D和抗C的情况下自行鉴定了抗G抗体，具有rr表型和primigravida名称的人。在第一次产前检查时完成抗体筛查后，我们建议母亲在将来可能怀孕时预防性抗D.
