PDF(Pubmed)
Abstract：
History of first-degree relatives with colorectal cancer is one of the most important and common risk factors for colorectal cancer in China. Most chronic diseases, such as malignancies, are preventable by adopting health-promoting behaviors and other approaches. However, the relationships among factors affecting the health-promoting lifestyles of first-degree relatives with colorectal cancer have not been sufficiently studied. This study aimed to test the mediation effects of Health belief in the relationship between health-promoting lifestyle and health information literacy among first-degree relatives with colorectal cancer.
A cross-sectional descriptive design was conducted using convenience sampling of 856 first-degree relatives of CRC patients attending three tertiary care hospitals in Nanchong and Deyang of China from December 2020 to December 2022. Questionnaires were used to collect data on the participants\' demographic information, the colorectal cancer health beliefs, the health promotion lifestyle, and the health information literacy. Data were analyzed with descriptive statistics, one-way ANOVA, Pearson\'s correlation coefficients, and mediation analysis using SPSS 25.0 program and its macro-program PROCESS.
The findings indicated health information literacy was less, health belief was at the medium level, and performance of health promotion behavior was average for first-degree relatives of colorectal cancer. Whereas first-degree relatives of colorectal cancer health-promotion lifestyle had a positive correlation with health beliefs (r = 0.376, p < 0.01) and health information literacy (r = 0.533, p < 0.01), health beliefs had a positive correlation with health information literacy (r = 0.337, p < 0.01). Health beliefs mediated the positive effect of health information literacy on health-promoting lifestyles (β =0.420, 95% CI, 0.288-0.581), and indirect effects accounted for 14.0% of the total effect.
Health information literacy and health beliefs are key factors associated with a health-promoting lifestyle among first-degree relatives with colorectal cancer. These factors have direct and indirect effects on each other and on health-promoting lifestyles. To enhance health-promoting lifestyles among first-degree relatives with colorectal cancer, interventions that strengthen health beliefs and provide health information literacy should be developed.
A cross-sectional descriptive design was conducted using convenience sampling of 856 first-degree relatives of CRC patients attending three tertiary care hospitals in Nanchong and Deyang of China from December 2020 to December 2022. Questionnaires were used to collect data on the participants\' demographic information, the colorectal cancer health beliefs, the health promotion lifestyle, and the health information literacy. Data were analyzed with descriptive statistics, one-way ANOVA, Pearson\'s correlation coefficients, and mediation analysis using SPSS 25.0 program and its macro-program PROCESS.
The findings indicated health information literacy was less, health belief was at the medium level, and performance of health promotion behavior was average for first-degree relatives of colorectal cancer. Whereas first-degree relatives of colorectal cancer health-promotion lifestyle had a positive correlation with health beliefs (r = 0.376, p < 0.01) and health information literacy (r = 0.533, p < 0.01), health beliefs had a positive correlation with health information literacy (r = 0.337, p < 0.01). Health beliefs mediated the positive effect of health information literacy on health-promoting lifestyles (β =0.420, 95% CI, 0.288-0.581), and indirect effects accounted for 14.0% of the total effect.
Health information literacy and health beliefs are key factors associated with a health-promoting lifestyle among first-degree relatives with colorectal cancer. These factors have direct and indirect effects on each other and on health-promoting lifestyles. To enhance health-promoting lifestyles among first-degree relatives with colorectal cancer, interventions that strengthen health beliefs and provide health information literacy should be developed.
摘要：
结直肠癌一级亲属病史是中国结直肠癌最重要和最常见的危险因素之一。大多数慢性疾病,比如恶性肿瘤，通过采取促进健康的行为和其他方法是可以预防的。然而,影响结直肠癌一级亲属健康促进生活方式的因素之间的关系尚未得到充分研究.这项研究旨在测试健康信念在大肠癌一级亲属中促进健康的生活方式与健康信息素养之间的关系中的调解作用。
从2020年12月至2022年12月，对中国南充和德阳三家三级医院就诊的856名CRC患者一级亲属进行了方便抽样，进行了横断面描述性设计。问卷调查被用来收集参与者的人口统计信息，大肠癌的健康信念，促进健康的生活方式，和健康信息素养。数据采用描述性统计分析，单向方差分析,皮尔逊相关系数，并使用SPSS25.0程序及其宏程序过程进行中介分析。
调查结果表明，健康信息素养较低，健康信念处于中等水平，结直肠癌一级亲属的健康促进行为表现平均。而结直肠癌一级亲属健康促进生活方式与健康信念(r=0.376,p<0.01)和健康信息素养(r=0.533,p<0.01)呈正相关,健康信念与健康信息素养呈正相关(r=0.337,p<0.01)。健康信念介导了健康信息素养对健康促进生活方式的积极影响（β=0.420，95％CI，0.288-0.581）。间接效应占总效应的14.0%。
健康信息素养和健康信念是与结直肠癌一级亲属的健康促进生活方式相关的关键因素。这些因素对彼此和促进健康的生活方式有直接和间接的影响。为了改善结直肠癌一级亲属的健康促进生活方式，应制定加强健康信念和提供健康信息素养的干预措施。
从2020年12月至2022年12月，对中国南充和德阳三家三级医院就诊的856名CRC患者一级亲属进行了方便抽样，进行了横断面描述性设计。问卷调查被用来收集参与者的人口统计信息，大肠癌的健康信念，促进健康的生活方式，和健康信息素养。数据采用描述性统计分析，单向方差分析,皮尔逊相关系数，并使用SPSS25.0程序及其宏程序过程进行中介分析。
调查结果表明，健康信息素养较低，健康信念处于中等水平，结直肠癌一级亲属的健康促进行为表现平均。而结直肠癌一级亲属健康促进生活方式与健康信念(r=0.376,p<0.01)和健康信息素养(r=0.533,p<0.01)呈正相关,健康信念与健康信息素养呈正相关(r=0.337,p<0.01)。健康信念介导了健康信息素养对健康促进生活方式的积极影响（β=0.420，95％CI，0.288-0.581）。间接效应占总效应的14.0%。
健康信息素养和健康信念是与结直肠癌一级亲属的健康促进生活方式相关的关键因素。这些因素对彼此和促进健康的生活方式有直接和间接的影响。为了改善结直肠癌一级亲属的健康促进生活方式，应制定加强健康信念和提供健康信息素养的干预措施。
