PDF(Pubmed)
Abstract：
Hypodontia is an inherited condition involving the absence of one to six teeth. The permanent dentition is the most frequently affected; however, it may also affect the primary dentition. A congenitally missing tooth (CMT) is the most common dental abnormality, with the missing mandibular second premolar, maxillary lateral incisor, maxillary second premolar, and mandibular central incisor accounting for 90% of CMT in hypodontia studies. The etiology of CMT has been attributed to environmental and genetic contributing factors, with the latter having a strong influence. It may occur in isolation or in association with syndromes. Congenitally missing mandibular incisor is more common in the Asian population and females. Depending on the number and location of missing teeth, hypodontia may be a considerable issue for the clinician since it may impact occlusal balance, mastication, speech, and esthetics and often requires a multidisciplinary approach. Missing mandibular incisors are of particular interest to orthodontists because of the possibility of mandibular retrognathism, the potential for the development of malocclusion, and difficulty in achieving a balanced occlusion. This case report describes the skeletal and dental features of a nonsyndromic familial occurrence of missing mandibular incisors in three generations. A comprehensive literature search was also performed to review the familial cases with missing mandibular incisors.
UNASSIGNED: Selvaraj M, Sennimalai K, Samrit VD, et al. A Rare Incidence of Nonsyndromic Mandibular Incisor Agenesis in a Three-generation Family: Case Report and Literature Review. Int J Clin Pediatr Dent 2023;16(2):388-395.
UNASSIGNED: Selvaraj M, Sennimalai K, Samrit VD, et al. A Rare Incidence of Nonsyndromic Mandibular Incisor Agenesis in a Three-generation Family: Case Report and Literature Review. Int J Clin Pediatr Dent 2023;16(2):388-395.
摘要：
缺牙症是一种遗传性疾病，涉及缺少一到六个牙齿。恒牙是最常见的影响;然而，它也可能影响原发性牙列。先天性牙齿缺失（CMT）是最常见的牙齿异常，下颌第二前磨牙缺失,上颌侧切牙,上颌第二前磨牙,下颌中切牙占CMT的90％。CMT的病因已归因于环境和遗传因素，后者具有强大的影响力。它可能孤立地发生或与综合征有关。先天性下颌切牙缺失在亚洲人群和女性中更为常见。根据缺牙的数量和位置，对于临床医生来说，牙髓不足可能是一个相当大的问题，因为它可能会影响咬合平衡，咀嚼,演讲,和美学，往往需要多学科的方法。下颌切牙缺失是正畸医生特别感兴趣的，因为下颌后颌畸形的可能性，发展错牙合的可能性，并且难以实现平衡的遮挡。此病例报告描述了三代下颌切牙缺失的非综合征性家族性发生的骨骼和牙齿特征。还进行了全面的文献检索，以回顾下颌切牙缺失的家族性病例。
■SelvarajM,SennimalaiK,SamritVD,etal.三代家庭中罕见的非综合征性下颌骨切断术：病例报告和文献综述。IntJClinPediatrDent2023；16（2）：388-395。
■SelvarajM,SennimalaiK,SamritVD,etal.三代家庭中罕见的非综合征性下颌骨切断术：病例报告和文献综述。IntJClinPediatrDent2023；16（2）：388-395。
