Abstract:
Lead (Pb), an environmental pollutant, has been widely reported to have contaminated mammals, including humans and birds. This study focuses on the effects of Pb pollution on avian influenza virus (AIV) antibody production. A total of 170 black-headed gulls (Chroicocephalus ridibundus) were captured in Tokyo Bay (TBP) from January 2019 to April 2020 and in Mikawa Bay (MBP) from November 2019 to April 2021. The gulls were weighed, subjected to blood sampling, and released with a ring band on their tarsus. The samples were used to measure blood Pb levels (BLL) and AIV-specific antibodies. The BLL were compared using the Wilcoxon two-sample test between the period when black-headed gulls arrived and the wintering period, defined by the number of gulls counted in each area. A significant increase was found in the TBP. A decrease in BLL significantly increased antibody titer during wintering in TBP and MBP. Pb pollution had a negative effect on the production of AIV antibodies. These findings suggest that wild birds that were contaminated by Pb in the environment may facilitate the spread of zoonotic diseases, further increasing the possibility that environmental pollutants may threaten human health.
摘要:
铅(Pb),一种环境污染物,已经被广泛报道污染了哺乳动物,包括人类和鸟类。本研究的重点是铅污染对禽流感病毒(AIV)抗体产生的影响。从2019年1月至2020年4月,在东京湾(TBP)和2019年11月至2021年4月在三川湾(MBP)共捕获了170只黑头海鸥(Chroicocephalusridibundus)。海鸥被称重,接受血液采样,并在他们的tarsus上带着环带释放。样品用于测量血液Pb水平(BLL)和AIV特异性抗体。在黑头海鸥到达的时期和越冬时期之间,使用Wilcoxon双样本检验比较了BLL,由每个区域计数的海鸥数量定义。发现TBP显著增加。在TBP和MBP越冬期间,BLL的降低显着增加了抗体滴度。铅污染对AIV抗体的产生有负面影响。这些发现表明,在环境中受到铅污染的野生鸟类可能会促进人畜共患疾病的传播,进一步增加了环境污染物威胁人类健康的可能性。