关键词: Haiti Vibrio cholerae antibodies bacteria cholera correlates of protection dried blood spots enteric infections outbreaks serosurveys vibriocidal

Mesh : Child Humans Child, Preschool Cholera / epidemiology Haiti / epidemiology Antibodies, Bacterial Vibrio cholerae O1 / genetics Disease Outbreaks

来  源:   DOI:10.3201/eid2909.230174   PDF(Pubmed)

Abstract:
A Vibrio cholerae O1 outbreak emerged in Haiti in October 2022 after years of cholera absence. In samples from a 2021 serosurvey, we found lower circulating antibodies against V. cholerae lipopolysaccharide in children <5 years of age and no vibriocidal antibodies, suggesting high susceptibility to cholera, especially among young children.
摘要:
在霍乱缺席多年之后,2022年10月在海地爆发了霍乱弧菌O1。在2021年血清调查的样本中,我们在<5岁的儿童中发现了较低的循环抗霍乱弧菌脂多糖抗体,并且没有抗弧菌抗体。表明对霍乱的高度易感性,尤其是在年幼的孩子中。
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