PDF(Pubmed)
Abstract：
Polyetheretherketone (PEEK) has been widely used in the medical field as an implant material, especially in bone tissue engineering and orthopedic surgery, in recent years. This material exhibits superior stability at high temperatures and is biosecured without harmful reactions. However, the chemical and biological inertness of PEEK still limits its applications. Recently, many approaches have been applied to improve its performance, including the modulation of physical morphology, chemical composition and antimicrobial agents, which advanced the osteointegration as well as antibacterial properties of PEEK materials. Based on the evolution of PEEK biomedical devices, many studies on the use of PEEK implants in spine surgery, joint surgery and trauma repair have been performed in the past few years, in most of which PEEK implants show better outcomes than traditional metal implants. This paper summarizes recent studies on the modification and application of biomedical PEEK materials, which provides further research directions for PEEK implants.
摘要：
聚醚醚酮(PEEK)作为植入材料已广泛应用于医疗领域,特别是在骨组织工程和骨科手术中，近年来。这种材料在高温下表现出优异的稳定性，并且是生物安全的，没有有害的反应。然而,PEEK的化学和生物惰性仍然限制了其应用。最近,已经应用了许多方法来提高其性能，包括物理形态的调制，化学成分和抗菌剂，这提高了PEEK材料的骨整合和抗菌性能。基于PEEK生物医学设备的发展，许多关于PEEK植入物在脊柱外科中使用的研究，在过去的几年中已经进行了关节手术和创伤修复，其中大多数PEEK植入物显示出比传统金属植入物更好的结果。本文综述了近年来医用PEEK材料的改性和应用研究,为PEEK植入物的进一步研究提供了方向。
