Abstract：
BACKGROUND: Among prostate cancer, primary prostate squamous cell carcinoma (SCC) is a rare condition with low incidence, and secondary prostate SCC is rarer with fewer cases reported globally. This report presents an extremely rare case of secondary prostate SCC that metastasised from lung cancer.
METHODS: This study reports the case of a 77-year-old man who presented with acute urinary retention and dysuria and was admitted to our hospital. Physical and digital rectal examinations were conducted and revealed the overfilling of the suprapubic bladder and a slightly enlarged prostate without palpable nodules, respectively. The patient was tested negative for total and free prostate antigens (PSA) and had large masses in the upper lobes of both lungs and an irregularly enlarged prostate in the computed tomography images. The patient was inserted immediately with 18F triple-cavity Foley catheter to drain haematuria with blood clots. The patient was treated with electric coagulation haemostasis and transurethral resection of the prostate and subjected to postoperative histopathological analysis, which revealed the diagnosis of SCC. The patient was advised to undergo further radiation therapy and chemotherapy but rejected all follow-up treatments for lungs and prostate. The patient recovered uneventfully and was discharged 7 days after the operation. The patient remained alive after 6 months of follow-up.
CONCLUSIONS: Secondary prostate SCC is an extremely rare type of tumour. Surgical intervention plays a role in stopping bleeding and relieving urination problems, and timely treatment may led to favourable prognosis.
METHODS: This study reports the case of a 77-year-old man who presented with acute urinary retention and dysuria and was admitted to our hospital. Physical and digital rectal examinations were conducted and revealed the overfilling of the suprapubic bladder and a slightly enlarged prostate without palpable nodules, respectively. The patient was tested negative for total and free prostate antigens (PSA) and had large masses in the upper lobes of both lungs and an irregularly enlarged prostate in the computed tomography images. The patient was inserted immediately with 18F triple-cavity Foley catheter to drain haematuria with blood clots. The patient was treated with electric coagulation haemostasis and transurethral resection of the prostate and subjected to postoperative histopathological analysis, which revealed the diagnosis of SCC. The patient was advised to undergo further radiation therapy and chemotherapy but rejected all follow-up treatments for lungs and prostate. The patient recovered uneventfully and was discharged 7 days after the operation. The patient remained alive after 6 months of follow-up.
CONCLUSIONS: Secondary prostate SCC is an extremely rare type of tumour. Surgical intervention plays a role in stopping bleeding and relieving urination problems, and timely treatment may led to favourable prognosis.
摘要：
背景：在前列腺癌中，原发性前列腺鳞状细胞癌（SCC）是一种罕见的低发病率，继发性前列腺SCC较罕见,全球报告的病例较少。本报告介绍了一种极为罕见的继发性前列腺SCC病例，该病例由肺癌转移。
方法：本研究报告1例77岁男性急性尿潴留和排尿困难入院。进行了身体检查和直肠指检,发现耻骨上膀胱过充,前列腺稍肿大,无明显结节,分别。该患者的总前列腺抗原和游离前列腺抗原（PSA）检测均为阴性，并且在计算机断层扫描图像中，两肺上叶肿块大，前列腺不规则增大。患者立即插入18F三腔Foley导管，以引流血尿并伴有血凝块。患者行电凝止血及经尿道前列腺电切术治疗,术后进行组织病理学分析,这揭示了SCC的诊断。建议患者接受进一步的放射治疗和化疗，但拒绝所有肺和前列腺的后续治疗。患者恢复顺利，术后7天出院。随访6个月后，患者仍存活。
结论：继发性前列腺SCC是一种极为罕见的肿瘤。手术干预在止血和缓解排尿问题方面发挥作用，及时治疗可能导致良好的预后。
方法：本研究报告1例77岁男性急性尿潴留和排尿困难入院。进行了身体检查和直肠指检,发现耻骨上膀胱过充,前列腺稍肿大,无明显结节,分别。该患者的总前列腺抗原和游离前列腺抗原（PSA）检测均为阴性，并且在计算机断层扫描图像中，两肺上叶肿块大，前列腺不规则增大。患者立即插入18F三腔Foley导管，以引流血尿并伴有血凝块。患者行电凝止血及经尿道前列腺电切术治疗,术后进行组织病理学分析,这揭示了SCC的诊断。建议患者接受进一步的放射治疗和化疗，但拒绝所有肺和前列腺的后续治疗。患者恢复顺利，术后7天出院。随访6个月后，患者仍存活。
结论：继发性前列腺SCC是一种极为罕见的肿瘤。手术干预在止血和缓解排尿问题方面发挥作用，及时治疗可能导致良好的预后。
