PDF(Pubmed)
Abstract：
OBJECTIVE: Secondary constipation refers to constipation that occurs after certain diseases or medications, such as acute stroke or opioids, and the efficacy of electroacupuncture for secondary constipation is controversial. So, this study aimed to explore the efficacy and safety of electroacupuncture for secondary constipation through a meta-analysis and systematic review.
METHODS: We retrieved articles from PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, and VIP databases up to 28 February 2023. The study was screened strictly according to inclusion and exclusion criteria. Revman5.4 was used for quality evaluation; grade rating was used for index evaluation, and stata15.0 was used for data consolidation analysis.
RESULTS: Thirteen randomized controlled studies, involving a total of 1437 people (722 electroacupuncture and 715 control groups), were included in this review. Meta-analysis results indicated that electroacupuncture significantly improved constipation overall response (RR = 1.31, 95%CI: 1.11, 1.55, P < 0.001), reduced defecation straining score (MD = - 0.46, 95%CI: - 0.67, - 0.251, P < 0.001), increased weekly complete spontaneous bowel movements (MD = 0.41, 95%CI: 0.20, 0.63, P = 0.002), and increased in the weekly spontaneous bowel movements (MD = 0.80, 95%CI (0.49, 01.11), P < 0.001), and electroacupuncture had no effect on change stool consistency score compared (MD = - 0.03, 95%CI (- 0.38, 0.33), P = 0.88) and did not increase adverse events (RR = 0.50, 95%CI: 0.18, 1.44, P = 0.20).
CONCLUSIONS: According to the current studies, the overall relief rate of patients with secondary constipation after electroacupuncture treatment was improved, the defecation pressure score was reduced, the weekly natural defecation was more complete, and adverse reactions were not increased. Electroacupuncture therefore shows potential for treating constipation, but more high-quality studies are needed to confirm these findings.
METHODS: We retrieved articles from PubMed, Embase, Cochrane Library, Web of Science, CNKI, Wanfang, and VIP databases up to 28 February 2023. The study was screened strictly according to inclusion and exclusion criteria. Revman5.4 was used for quality evaluation; grade rating was used for index evaluation, and stata15.0 was used for data consolidation analysis.
RESULTS: Thirteen randomized controlled studies, involving a total of 1437 people (722 electroacupuncture and 715 control groups), were included in this review. Meta-analysis results indicated that electroacupuncture significantly improved constipation overall response (RR = 1.31, 95%CI: 1.11, 1.55, P < 0.001), reduced defecation straining score (MD = - 0.46, 95%CI: - 0.67, - 0.251, P < 0.001), increased weekly complete spontaneous bowel movements (MD = 0.41, 95%CI: 0.20, 0.63, P = 0.002), and increased in the weekly spontaneous bowel movements (MD = 0.80, 95%CI (0.49, 01.11), P < 0.001), and electroacupuncture had no effect on change stool consistency score compared (MD = - 0.03, 95%CI (- 0.38, 0.33), P = 0.88) and did not increase adverse events (RR = 0.50, 95%CI: 0.18, 1.44, P = 0.20).
CONCLUSIONS: According to the current studies, the overall relief rate of patients with secondary constipation after electroacupuncture treatment was improved, the defecation pressure score was reduced, the weekly natural defecation was more complete, and adverse reactions were not increased. Electroacupuncture therefore shows potential for treating constipation, but more high-quality studies are needed to confirm these findings.
摘要：
目的：继发性便秘是指某些疾病或药物治疗后发生的便秘，如急性中风或阿片类药物，电针治疗继发性便秘的疗效存在争议。所以,本研究旨在通过荟萃分析和系统评价探讨电针治疗继发性便秘的有效性和安全性。
方法：我们从PubMed检索了文章，Embase,科克伦图书馆,WebofScience,CNKI,万方,和VIP数据库，截至2023年2月28日。本研究严格按照纳入和排除标准进行筛选。Revman5.4用于质量评价；等级等级用于指标评价，stata15.0用于数据整合分析。
结果：13项随机对照研究，共有1437人(722个电针组和715个对照组)，包括在这次审查中。Meta分析结果显示,电针可显著改善便秘的总体反应(RR=1.31,95CI:1.11,1.55,P<0.001),减少排便疲劳评分（MD=-0.46，95CI：-0.67，-0.251，P<0.001），每周完全自发排便增加（MD=0.41，95CI：0.20，0.63，P=0.002），每周自发排便增加（MD=0.80,95CI（0.49,01.11），P<0.001)，电针对大便稠度评分的改变无影响(MD=-0.03,95CI(-0.38,0.33),P=0.88），并且没有增加不良事件（RR=0.50，95CI：0.18，1.44，P=0.20）。
结论：根据目前的研究，电针治疗后继发性便秘患者的总体缓解率提高,排便压力评分降低，每周自然排便更完整，不良反应未增加。因此，电针显示出治疗便秘的潜力，但需要更多高质量的研究来证实这些发现。
方法：我们从PubMed检索了文章，Embase,科克伦图书馆,WebofScience,CNKI,万方,和VIP数据库，截至2023年2月28日。本研究严格按照纳入和排除标准进行筛选。Revman5.4用于质量评价；等级等级用于指标评价，stata15.0用于数据整合分析。
结果：13项随机对照研究，共有1437人(722个电针组和715个对照组)，包括在这次审查中。Meta分析结果显示,电针可显著改善便秘的总体反应(RR=1.31,95CI:1.11,1.55,P<0.001),减少排便疲劳评分（MD=-0.46，95CI：-0.67，-0.251，P<0.001），每周完全自发排便增加（MD=0.41，95CI：0.20，0.63，P=0.002），每周自发排便增加（MD=0.80,95CI（0.49,01.11），P<0.001)，电针对大便稠度评分的改变无影响(MD=-0.03,95CI(-0.38,0.33),P=0.88），并且没有增加不良事件（RR=0.50，95CI：0.18，1.44，P=0.20）。
结论：根据目前的研究，电针治疗后继发性便秘患者的总体缓解率提高,排便压力评分降低，每周自然排便更完整，不良反应未增加。因此，电针显示出治疗便秘的潜力，但需要更多高质量的研究来证实这些发现。
