PDF(Pubmed)
Abstract：
Adansonia digitata L. fruit, also known as baobab, has been used traditionally throughout the world for its medicinal properties. Ethnopharmacological uses of various plant parts have been reported for hydration, antipyretic, antiparasitic, antitussive, and sudorific properties and also in the treatment of diarrhea and dysentery in many African countries. Several studies have revealed that in addition to these applications, baobab has antioxidant, anti-inflammatory, analgesic, and antimicrobial activities. The health benefits of baobab have been attributed to its bioactive compounds, namely phenols, flavonoids, proanthocyanins, tannins, catechins, and carotenoids. Baobab fruit is also an important source of vitamin C and micronutrients, including zinc, potassium, magnesium, iron, calcium, and protein, which may reduce nutritional deficiencies. Despite scientific studies revealing that this fruit has a wide diversity of bioactive compounds with beneficial effects on health, there is a gap in the review of information about their mechanisms of action and critical analysis of clinical trials exploring, in particular, their effect on glycemia regulation. This work aims to present a current overview of the bioactive compounds, biological activities, and effects of A. digitata fruit on blood glucose, highlighting their potential mechanisms of action and effects on glycemia regulation, evaluated in recent animal and human trials.
摘要：
洋地黄L.水果，也被称为猴面包树，由于其药用特性，在世界各地一直被传统地使用。据报道，各种植物部位的民族药理学用途用于水合作用，退烧药,抗寄生虫，镇咳,以及许多非洲国家的腹泻和痢疾的治疗。一些研究表明，除了这些应用之外，猴面包树有抗氧化剂，抗炎,镇痛药,和抗菌活性。猴面包树的健康益处归因于其生物活性化合物，即酚类，黄酮类化合物，原花青素,单宁,儿茶素,和类胡萝卜素。猴面包树果实也是维生素C和微量营养素的重要来源，包括锌,钾，镁，铁,钙，和蛋白质,这可以减少营养缺乏。尽管科学研究表明这种水果具有多种生物活性化合物，对健康有益，在审查有关其作用机制的信息和对临床试验探索的批判性分析方面存在差距，特别是,它们对血糖调节的影响。这项工作旨在介绍生物活性化合物的最新概况，生物活动，以及洋地黄果实对血糖的影响，强调其潜在的作用机制和对血糖调节的影响，在最近的动物和人体试验中进行了评估。
