PDF(Pubmed)
Abstract：
The Riddoch syndrome is one in which patients blinded by lesions to their primary visual cortex can consciously perceive visual motion in their blind field, an ability that correlates with activity in motion area V5. Our assessment of the characteristics of this syndrome in patient ST, using multimodal MRI, showed that: 1. ST\'s V5 is intact, receives direct subcortical input, and decodable neural patterns emerge in it only during the conscious perception of visual motion; 2. moving stimuli activate medial visual areas but, unless associated with decodable V5 activity, they remain unperceived; 3. ST\'s high confidence ratings when discriminating motion at chance levels, is associated with inferior frontal gyrus activity. Finally, we report that ST\'s Riddoch Syndrome results in hallucinatory motion with hippocampal activity as a correlate. Our results shed new light on perceptual experiences associated with this syndrome and on the neural determinants of conscious visual experience.
摘要：
Riddoch综合征是一种由于初级视觉皮层病变而失明的患者可以有意识地感知盲区中的视觉运动，与运动区域V5中的活动相关的能力。我们对ST患者的这种综合征特征的评估，使用多模态MRI，表明：1。ST\的V5完好无损,接收直接的皮层下输入，只有在有意识地感知视觉运动时，才会出现可解码的神经模式；2.移动刺激激活内侧视觉区域，但是，除非与可解码的V5活动相关联，他们没有被发现；3。在机会级别区分运动时，ST的高置信度等级，与额下回活动有关。最后,我们报道ST’sRiddoch综合征导致幻觉运动与海马活动相关。我们的结果为与该综合征相关的感知体验以及有意识的视觉体验的神经决定因素提供了新的思路。
