关键词: Antipsychotic agent Evidence-based practice Guideline Hyperprolactinemia

来  源:   DOI:10.9758/cpn.22.979   PDF(Pubmed)

Abstract:
UNASSIGNED: To develop an evidence-based guideline for the diagnosis and treatment of antipsychotic-induced hyperprolactinemia by adapting existing high-quality clinical guidelines with a view to improve the clinical symptoms and long-term quality of life of patients by providing appropriate management.
UNASSIGNED: This guideline was developed according to the ADAPTE methodology. The adaptation process included determining key health questions, systematically searching and screening guidelines, evaluating the quality and contents of these guidelines, deriving recommendations for key questions, and performing a peer review. The selection criteria for the guideline search were (1) evidence-based guidelines, (2) published within the last 5 years, and (3) written in English or Korean.
UNASSIGNED: After evaluating the quality and content, we finally selected three guidelines for adaptation. The final output of the development process was 25 recommendations for 10 key questions. We adopted the Agency for Health Research Quality methodology and presented the level of evidence from levels I to IV. In addition, we defined the recommendation grades from grade A (strongly recommended) to D (no recommendation) based on the level of evidence and clinical significance of the recommendation.
UNASSIGNED: The development and dissemination of the adapted guideline is expected to increase the certainty of medical decision making and improve the quality of medical care. Further studies on the effectiveness and applicability of the developed guideline are necessary.
摘要:
通过调整现有的高质量临床指南,为抗精神病药物引起的高催乳素血症的诊断和治疗制定循证指南,以期通过提供适当的管理来改善患者的临床症状和长期生活质量。
本指南是根据ADAPTE方法制定的。适应过程包括确定关键的健康问题,系统地搜索和筛查指南,评估这些指南的质量和内容,为关键问题提供建议,并进行同行评审。指南搜索的选择标准是(1)基于证据的指南,(2)最近5年内出版的,(3)用英语或韩语书写。
在评估了质量和内容之后,我们最终选择了三个适应指南。开发过程的最终结果是针对10个关键问题的25项建议。我们采用了卫生研究质量机构的方法,并提出了从I级到IV级的证据水平。此外,我们根据推荐的证据水平和临床意义定义了从A级(强烈推荐)到D级(无推荐)的推荐等级.
适应指南的制定和传播有望提高医疗决策的确定性并提高医疗质量。有必要进一步研究制定的指南的有效性和适用性。
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