关键词: Conductos ecrinos Eccrine duct Infección viral Monkeypox Skin ulcer Viral infection Viruela del mono Úlcera cutánea

Mesh : Male Animals Humans Adult Mpox (monkeypox) / epidemiology Epithelium / chemistry DNA, Viral / analysis Diagnosis, Differential

来  源:   DOI:10.1016/j.patol.2023.01.001   PDF(Pubmed)

Abstract:
Monkeypox was historically considered a zoonotic disease restricted to areas with an animal reservoir and with limited possibilities of human transmission. However, the recent increase in incidence in non-endemic areas, together with the demonstration of human transmission, has led to more attention being paid to this disease. We present the case of a 27-year-old man with cutaneous lesions and perianal ulcers, clinically suggestive of a viral disease. Monkeypox was demonstrated with PCR analysis. The histological features and differential diagnoses of monkeypox are discussed and the characteristic histopathological pattern of eccrine gland epithelium is described which, if found in an ulcerated lesion, should raise suspicion of monkeypox.
摘要:
猴痘历史上被认为是一种人畜共患疾病,仅限于有动物水库的地区,人类传播的可能性有限。然而,最近非流行地区的发病率增加,连同人类传播的演示,引起了人们对这种疾病的更多关注。我们介绍了一个27岁的男性皮肤病变和肛周溃疡,临床上提示病毒性疾病。用PCR分析证明猴痘。讨论了猴痘的组织学特征和鉴别诊断,并描述了内分泌腺上皮的特征性组织病理学模式,如果在溃疡病变中发现,应该引起猴痘的怀疑.
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