Abstract：
Blood transfusion saves millions of lives year around the world; it is the most important life-saving option for blood recipients. However, this act is not without risks as contaminated blood may be the source of transfusion-transmissible infections (TTI). This is a retrospective and comparative study on the prevalence of acquired human immunodeficiency syndrome, viral hepatitis B, C and syphilis in blood donors from Bejaia province (Algeria).
This study is designed to estimate the risk of TTIs among blood donors and the demographic associated factors. It was carried out in the serology laboratories of Bejaia blood transfusion center and Khalil Amrane university hospital. Data were collected from the archived results of screening tests for HBV, HCV, HIV and syphilis, mandatory for all blood donations, from January 2010 to December 2019. The association was considered statistically significant at p < 0.05.
Among 140,168 donors from Bejaia province, 78,123 represent the urban population and 62,045 the rural population. Over 10 years, results of serological tests revealed a prevalence of 0.077%, 0.083%, 0.102%, and 0.132%, respectively for HIV, HCV, HBV, and Treponema pallidum. Trends of hepatitis B and syphilis were decreasing; however, hepatitis C was increasing.
HIV and syphilis prevalence have been variable, with significant peaks in 2013 and 2014, respectively. Globally, the low rates reported in this study confirm the effectiveness of the preventive policy applied by the health authorities. However, among the rural population, special attention is required to stem any resurgence of hepatitis C and syphilis.
This study is designed to estimate the risk of TTIs among blood donors and the demographic associated factors. It was carried out in the serology laboratories of Bejaia blood transfusion center and Khalil Amrane university hospital. Data were collected from the archived results of screening tests for HBV, HCV, HIV and syphilis, mandatory for all blood donations, from January 2010 to December 2019. The association was considered statistically significant at p < 0.05.
Among 140,168 donors from Bejaia province, 78,123 represent the urban population and 62,045 the rural population. Over 10 years, results of serological tests revealed a prevalence of 0.077%, 0.083%, 0.102%, and 0.132%, respectively for HIV, HCV, HBV, and Treponema pallidum. Trends of hepatitis B and syphilis were decreasing; however, hepatitis C was increasing.
HIV and syphilis prevalence have been variable, with significant peaks in 2013 and 2014, respectively. Globally, the low rates reported in this study confirm the effectiveness of the preventive policy applied by the health authorities. However, among the rural population, special attention is required to stem any resurgence of hepatitis C and syphilis.
摘要：
背景：输血每年在世界各地挽救数百万人的生命；它是受血者最重要的挽救生命的选择。然而,这一行为并非没有风险,因为受污染的血液可能是输血传播感染(TTI)的来源.这是一项关于获得性免疫机能丧失综合症患病率的回顾性及比较研究,病毒性乙型肝炎，来自Bejaia省（阿尔及利亚）的献血者的C和梅毒。
方法：本研究旨在评估献血者中发生TTI的风险和人口统计学相关因素。它是在Bejaia输血中心和KhalilAmrane大学医院的血清学实验室进行的。数据是从HBV筛查试验的存档结果中收集的，HCV,艾滋病毒和梅毒，所有献血都是强制性的，从2010年1月到2019年12月。该关联在p<0.05时被认为是统计学上显著的。
结果：在来自贝贾亚省的140,168名捐赠者中，城市人口为78,123，农村人口为62,045。超过10年,血清学检测结果显示患病率为0.077%，0.083%,0.102%，和0.132%，分别为艾滋病毒，HCV,HBV,和梅毒螺旋体.乙型肝炎和梅毒的趋势正在下降；然而，丙型肝炎正在增加。
结论：HIV和梅毒的患病率是可变的，分别在2013年和2014年达到显著峰值。全球范围内,本研究报告的低发病率证实了卫生当局实施的预防政策的有效性.然而,在农村人口中，需要特别注意阻止丙型肝炎和梅毒的复发。
方法：本研究旨在评估献血者中发生TTI的风险和人口统计学相关因素。它是在Bejaia输血中心和KhalilAmrane大学医院的血清学实验室进行的。数据是从HBV筛查试验的存档结果中收集的，HCV,艾滋病毒和梅毒，所有献血都是强制性的，从2010年1月到2019年12月。该关联在p<0.05时被认为是统计学上显著的。
结果：在来自贝贾亚省的140,168名捐赠者中，城市人口为78,123，农村人口为62,045。超过10年,血清学检测结果显示患病率为0.077%，0.083%,0.102%，和0.132%，分别为艾滋病毒，HCV,HBV,和梅毒螺旋体.乙型肝炎和梅毒的趋势正在下降；然而，丙型肝炎正在增加。
结论：HIV和梅毒的患病率是可变的，分别在2013年和2014年达到显著峰值。全球范围内,本研究报告的低发病率证实了卫生当局实施的预防政策的有效性.然而,在农村人口中，需要特别注意阻止丙型肝炎和梅毒的复发。
