PDF(Pubmed)
Abstract：
BACKGROUND: Eosinophilic granuloma (EG) - the most common form of Langerhans cell histiocytosis - occurs rarely, and manifestations with only rib and clavicle involvement are extremely rare. EG symptoms often include pain, swelling, and soft tissue mass. The clinical diagnosis of bone EG is complex, and the differential diagnosis includes Ewing sarcoma, tuberculosis, multiple myeloma, lymphoma, primary bone malignancy, and other osteolytic lesions.
METHODS: The patient was an 11-year-old female who found a subcutaneous mass at the junction of the right clavicle and sternum 2 days before presenting at the clinic without apparent triggers. Initially, we considered a subcutaneous cyst or inflammatory mass. Color ultrasound and computed tomography examination revealed osteomyelitis. Finally, the patient was diagnosed with EG after a pathological tissue biopsy, and the child recovered after surgery and anti-infective treatment.
METHODS: The patient underwent surgery to remove the tumor at a specialist hospital and was diagnosed with EG by pathological examination.
METHODS: The patient went to a specialist hospital for surgery to remove the mass and underwent anti-infective treatment.
RESULTS: The patient recovered after surgical resection and antibiotic treatment.
CONCLUSIONS: In this report, we emphasize that the clinical presentation of EG in children is not specific. Furthermore, examining age, history, presence of symptoms, and the number of sites is essential to make a correct diagnosis, and a histological examination is necessary to confirm the diagnosis.
METHODS: The patient was an 11-year-old female who found a subcutaneous mass at the junction of the right clavicle and sternum 2 days before presenting at the clinic without apparent triggers. Initially, we considered a subcutaneous cyst or inflammatory mass. Color ultrasound and computed tomography examination revealed osteomyelitis. Finally, the patient was diagnosed with EG after a pathological tissue biopsy, and the child recovered after surgery and anti-infective treatment.
METHODS: The patient underwent surgery to remove the tumor at a specialist hospital and was diagnosed with EG by pathological examination.
METHODS: The patient went to a specialist hospital for surgery to remove the mass and underwent anti-infective treatment.
RESULTS: The patient recovered after surgical resection and antibiotic treatment.
CONCLUSIONS: In this report, we emphasize that the clinical presentation of EG in children is not specific. Furthermore, examining age, history, presence of symptoms, and the number of sites is essential to make a correct diagnosis, and a histological examination is necessary to confirm the diagnosis.
摘要：
背景：嗜酸性肉芽肿（EG）-朗格汉斯细胞组织细胞增生症的最常见形式-很少发生，仅肋骨和锁骨受累的表现极为罕见。EG症状通常包括疼痛，肿胀,和软组织肿块。骨EG的临床诊断复杂,鉴别诊断包括尤因肉瘤,结核病,多发性骨髓瘤,淋巴瘤原发性骨恶性肿瘤，和其他溶骨性病变。
方法：患者是一名11岁女性，在就诊前2天发现右锁骨和胸骨交界处皮下肿块，无明显诱因。最初，我们考虑皮下囊肿或炎性肿块。彩色超声和计算机断层扫描检查显示骨髓炎。最后,患者在病理组织活检后被诊断为EG，经手术和抗感染治疗后，患儿康复。
方法：患者在专科医院行手术切除肿瘤，经病理检查确诊为EG。
方法：患者到专科医院手术切除肿块，并接受抗感染治疗。
结果：患者在手术切除和抗生素治疗后康复。
结论：在本报告中，我们强调EG在儿童中的临床表现并不具有特异性.此外，检查年龄,历史,存在的症状，这些部位的数量对于做出正确的诊断至关重要，组织学检查是必要的，以确认诊断。
方法：患者是一名11岁女性，在就诊前2天发现右锁骨和胸骨交界处皮下肿块，无明显诱因。最初，我们考虑皮下囊肿或炎性肿块。彩色超声和计算机断层扫描检查显示骨髓炎。最后,患者在病理组织活检后被诊断为EG，经手术和抗感染治疗后，患儿康复。
方法：患者在专科医院行手术切除肿瘤，经病理检查确诊为EG。
方法：患者到专科医院手术切除肿块，并接受抗感染治疗。
结果：患者在手术切除和抗生素治疗后康复。
结论：在本报告中，我们强调EG在儿童中的临床表现并不具有特异性.此外，检查年龄,历史,存在的症状，这些部位的数量对于做出正确的诊断至关重要，组织学检查是必要的，以确认诊断。
