PDF(Pubmed)
Abstract：
Human skin pigmentation and melanin synthesis are incredibly variable, and are impacted by genetics, UV exposure, and some drugs. Patients\' physical appearance, psychological health, and social functioning are all impacted by a sizable number of skin conditions that cause pigmentary abnormalities. Hyperpigmentation, where pigment appears to overflow, and hypopigmentation, where pigment is reduced, are the two major classifications of skin pigmentation. Albinism, melasma, vitiligo, Addison\'s disease, and post-inflammatory hyperpigmentation, which can be brought on by eczema, acne vulgaris, and drug interactions, are the most common skin pigmentation disorders in clinical practice. Anti-inflammatory medications, antioxidants, and medications that inhibit tyrosinase, which prevents the production of melanin, are all possible treatments for pigmentation problems. Skin pigmentation can be treated orally and topically with medications, herbal remedies, and cosmetic products, but a doctor should always be consulted before beginning any new medicine or treatment plan. This review article explores the numerous types of pigmentation problems, their causes, and treatments, as well as the 25 plants, 4 marine species, and 17 topical and oral medications now on the market that have been clinically tested to treat skin diseases.
摘要：
人类皮肤色素沉着和黑色素合成是难以置信的变化，受到遗传学的影响，UV暴露,还有一些药物.患者的外表，心理健康,和社会功能都受到大量导致色素异常的皮肤状况的影响。色素沉着过度,颜料似乎溢出，和色素沉着减退，色素减少的地方，是皮肤色素沉着的两大分类。白化病,黄褐斑,白癜风,艾迪生的病,和炎症后色素沉着过度，这可能是由湿疹引起的，寻常痤疮,和药物相互作用，是临床实践中最常见的皮肤色素沉着障碍。抗炎药,抗氧化剂,和抑制酪氨酸酶的药物，防止黑色素的产生，都是色素沉着问题的可能治疗方法。皮肤色素沉着可以口服和局部用药物治疗，草药，和化妆品，但是在开始任何新药或治疗计划之前，应始终咨询医生。这篇综述文章探讨了多种类型的色素沉着问题，他们的原因,和治疗，以及25种植物，4种海洋物种，和17个局部和口服药物现在市场上已经过临床试验，以治疗皮肤病。
