PDF(Pubmed)
Abstract：
Pure titanium (Ti) is investigated in a pre-clinical study in Hank\'s biological solution using electrochemical methods, open circuit potential, and electrochemical impedance spectroscopy to highlight the time effect in extreme body conditions, such as inflammatory diseases, on degradability due to corrosion processes occurring on the titanium implant. Electrochemical impedance spectroscopy (EIS) data are presented as Nyquist and Bode plots. The results show the increasing reactivity of titanium implants in the presence of hydrogen peroxide, which is an oxygen-reactive compound that describes inflammatory conditions. The polarization resistance, which results from electrochemical impedance spectroscopy measurements, declined dramatically from the highest value registered in Hank\'s solution to smaller values registered in all solutions when different concentrations of hydrogen peroxide were tested. The EIS analysis provided insights into titanium\'s in vitro corrosion behavior as an implanted biomaterial, which could not be solely obtained through potentiodynamic polarization testing.
摘要：
纯钛（Ti）在Hank的生物溶液中使用电化学方法进行临床前研究，开路电位,和电化学阻抗谱来突出极端身体条件下的时间效应，如炎症性疾病，由于钛植入物上发生的腐蚀过程而导致的降解性。电化学阻抗谱(EIS)数据呈现为奈奎斯特和波特图。结果表明，在过氧化氢的存在下，钛植入物的反应性增加，它是描述炎症状态的氧反应性化合物。极化电阻，它来自电化学阻抗谱测量，当测试不同浓度的过氧化氢时，从汉克溶液中记录的最高值急剧下降到所有溶液中记录的较小值。EIS分析提供了对钛作为植入生物材料的体外腐蚀行为的见解，这不能单独通过动电位极化测试获得。
