Abstract：
Diagnosing and treating neonatal and infantile erythroderma can be challenging due to the wide variety of potential causes. Neonatal erythroderma is rare and is associated with a high mortality rate due to complications of erythroderma itself and potential life-threatening underlying diseases. Prolonged erythroderma should always be a warning sign and an indication for referral to a hospital where a multidisciplinary team approach is possible. The role of a pediatric dermatologist is to keep in mind the wide spectrum of differential diagnoses that could be causing the condition and the determination of the final diagnosis. To avert a delay in establishing the correct diagnosis, we suggest adhering to specific guidelines. We reviewed available guidelines and adapted a step-by-step approach for use in Slovenia. We also discuss a case of a neonate with erythroderma to illustrate the applicability of the proposed guidelines. Our patient presented with persistent erythroderma, pustules on the trunk and limbs, and intertriginous dermatitis. Despite local corticosteroid treatment, the skin redness persisted. After the exclusion of a systemic infection and additional tests, Omenn syndrome was diagnosed as the underlying cause.
摘要：
由于各种潜在原因，诊断和治疗新生儿和婴儿红皮病可能具有挑战性。新生儿红皮病很少见，并且由于红皮病本身的并发症和潜在的威胁生命的潜在疾病而导致高死亡率。长期的红皮病应始终是一个警告信号，并应转诊到可以采用多学科团队方法的医院。儿科皮肤科医生的作用是记住可能导致病情的广泛鉴别诊断和最终诊断的确定。为了避免延误建立正确的诊断，我们建议坚持具体的指导方针。我们审查了可用的指南，并采用了逐步的方法在斯洛文尼亚使用。我们还讨论了一例患有红皮病的新生儿，以说明拟议指南的适用性。我们的病人表现为持续性红皮病，躯干和四肢上的脓疱,和齿间性皮炎。尽管有局部皮质类固醇治疗,皮肤发红持续。在排除全身感染和额外测试后，Omenn综合征被诊断为根本原因。
