PDF(Pubmed)
Abstract：
BACKGROUND: Vivascope 2500 ex vivo confocal microscopy (EVCM) is an emerging optical imaging device that allows nuclear level resolution of freshly excised tissues. EVCM provides, rapid real-time pathological examination in many subspecialties of pathology including skin, prostate, breast, liver, etc. In contrast to traditional time-consuming frozen sectioning and histological analysis.
OBJECTIVE: To evaluate the current state of EVCM utilization.
METHODS: This study highlights the advantages, limitations, and prospects of EVCM in skin pathology.
RESULTS: Our findings demonstrate that EVCM is a promising adjunctive tool to assess margins in Mohs surgery and to provide rapid, accurate diagnosis of cutaneous tumors, infectious and inflammatory diseases.
CONCLUSIONS: EVCM is a revolutionary device that can be used as an adjunct to paraffin-fixed, hematoxylin and eosin-stained slides and frozen sectioning. Additional refinements are required before EVCM can be used as an alternative to frozen sectioning or traditional tissue processing.
OBJECTIVE: To evaluate the current state of EVCM utilization.
METHODS: This study highlights the advantages, limitations, and prospects of EVCM in skin pathology.
RESULTS: Our findings demonstrate that EVCM is a promising adjunctive tool to assess margins in Mohs surgery and to provide rapid, accurate diagnosis of cutaneous tumors, infectious and inflammatory diseases.
CONCLUSIONS: EVCM is a revolutionary device that can be used as an adjunct to paraffin-fixed, hematoxylin and eosin-stained slides and frozen sectioning. Additional refinements are required before EVCM can be used as an alternative to frozen sectioning or traditional tissue processing.
摘要：
背景：Vivascope2500离体共聚焦显微镜（EVCM）是一种新兴的光学成像设备，可实现新鲜切除组织的核水平分辨率。EVCM提供，在包括皮肤在内的许多病理亚专业中进行快速实时病理检查，前列腺,乳房,肝脏,等。与传统耗时的冷冻切片和组织学分析相反。
目的：评估EVCM的使用现状。
方法：本研究突出优点，局限性,以及EVCM在皮肤病理学中的应用前景。
结果：我们的研究结果表明，EVCM是评估Mohs手术边缘的一种有前途的辅助工具，皮肤肿瘤的准确诊断，传染性和炎症性疾病。
结论：EVCM是一种革命性的装置，可用作石蜡固定的附件，苏木精和伊红染色的载玻片和冷冻切片。在EVCM可以用作冷冻切片或传统组织处理的替代方法之前，需要进行其他改进。
目的：评估EVCM的使用现状。
方法：本研究突出优点，局限性,以及EVCM在皮肤病理学中的应用前景。
结果：我们的研究结果表明，EVCM是评估Mohs手术边缘的一种有前途的辅助工具，皮肤肿瘤的准确诊断，传染性和炎症性疾病。
结论：EVCM是一种革命性的装置，可用作石蜡固定的附件，苏木精和伊红染色的载玻片和冷冻切片。在EVCM可以用作冷冻切片或传统组织处理的替代方法之前，需要进行其他改进。
