%0 Journal Article
%T Role of VivaScope 2500 ex vivo confocal microscopy in skin pathology: Advantages, limitations, and future prospects.
%A Razi S
%A Ouellette S
%A Khan S
%A Oh KS
%A Truong TM
%A Rao BK
%J Skin Res Technol
%V 29
%N 6
%D 2023 Jun
%M 37357649
%F 2.24
%R 10.1111/srt.13388
%X <B>BACKGROUND: </B>Vivascope 2500 ex vivo confocal microscopy (EVCM) is an emerging optical imaging device that allows nuclear level resolution of freshly excised tissues. EVCM provides, rapid real-time pathological examination in many subspecialties of pathology including skin, prostate, breast, liver, etc. In contrast to traditional time-consuming frozen sectioning and histological analysis.<BR><B>OBJECTIVE: </B>To evaluate the current state of EVCM utilization.<BR><B>METHODS: </B>This study highlights the advantages, limitations, and prospects of EVCM in skin pathology.<BR><B>RESULTS: </B>Our findings demonstrate that EVCM is a promising adjunctive tool to assess margins in Mohs surgery and to provide rapid, accurate diagnosis of cutaneous tumors, infectious and inflammatory diseases.<BR><B>CONCLUSIONS: </B>EVCM is a revolutionary device that can be used as an adjunct to paraffin-fixed, hematoxylin and eosin-stained slides and frozen sectioning. Additional refinements are required before EVCM can be used as an alternative to frozen sectioning or traditional tissue processing.