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Abstract：
BACKGROUND: Colonoscopy is considered the most effective screening method for colorectal polyps. However, the longevity and complexity of the procedure makes it less desirable to screen for colorectal polyps in the general population. Therefore, it is essential to identify other independent risk factors. In this study, we explored the link between Hp infection, atrophic gastritis, and colorectal polyps to identify a new potential risk factors of colorectal polyps.
METHODS: In this study, atrophic gastritis and intestinal polyps were diagnosed by endoscopy and pathology. All the 792 patients in this retrospective study were divided into sub-groups based on the presence of colorectal polyps. The correlation between polyps and atrophic gastritis was analyzed using the chi-square test and Kruskal-Wallis test. The receiver operating characteristic (ROC) curve was used to compare the predictive value for colorectal polyps between Hp infection and atrophic gastritis. Binary logistic regression was utilized to identify independent risk factors for colorectal polyps.
RESULTS: Patients with colorectal polyps were primarily male with advanced age, and the number of patients with colorectal polyps had a higher association with smoking, alcohol drinking, and Hp infection than the control group. A positive correlation between the number of colorectal polyps and the severity of atrophic gastritis was observed. ROC analysis showed that atrophic gastritis was a better risk factors for colorectal polyps. Multivariate analysis identified atrophic gastritis as an independent risk factor for colorectal polyps (OR 2.294; 95% CI 1.597-3.296).
CONCLUSIONS: Atrophic gastritis confirmed could be an independent risk factors for colorectal polyps.
METHODS: In this study, atrophic gastritis and intestinal polyps were diagnosed by endoscopy and pathology. All the 792 patients in this retrospective study were divided into sub-groups based on the presence of colorectal polyps. The correlation between polyps and atrophic gastritis was analyzed using the chi-square test and Kruskal-Wallis test. The receiver operating characteristic (ROC) curve was used to compare the predictive value for colorectal polyps between Hp infection and atrophic gastritis. Binary logistic regression was utilized to identify independent risk factors for colorectal polyps.
RESULTS: Patients with colorectal polyps were primarily male with advanced age, and the number of patients with colorectal polyps had a higher association with smoking, alcohol drinking, and Hp infection than the control group. A positive correlation between the number of colorectal polyps and the severity of atrophic gastritis was observed. ROC analysis showed that atrophic gastritis was a better risk factors for colorectal polyps. Multivariate analysis identified atrophic gastritis as an independent risk factor for colorectal polyps (OR 2.294; 95% CI 1.597-3.296).
CONCLUSIONS: Atrophic gastritis confirmed could be an independent risk factors for colorectal polyps.
摘要：
背景：结肠镜检查被认为是结直肠息肉最有效的筛查方法。然而,该手术的寿命和复杂性使得在普通人群中筛查结直肠息肉不太可取.因此,确定其他独立的风险因素至关重要。在这项研究中,我们探索了Hp感染之间的联系，萎缩性胃炎,结直肠息肉新的潜在危险因素。
方法：在本研究中，胃镜和病理诊断为萎缩性胃炎和肠息肉。这项回顾性研究中的所有792例患者都根据结直肠息肉的存在分为亚组。采用卡方检验和Kruskal-Wallis检验分析息肉与萎缩性胃炎的相关性。采用受试者工作特征(ROC)曲线比较Hp感染与萎缩性胃炎对结直肠息肉的预测价值。采用二元Logistic回归分析确定结直肠息肉的独立危险因素。
结果：结直肠息肉患者主要为高龄男性，结直肠息肉患者的数量与吸烟有更高的相关性，饮酒,而Hp感染组优于对照组。观察到大肠息肉的数量与萎缩性胃炎的严重程度呈正相关。ROC分析显示萎缩性胃炎是大肠息肉较好的危险因素。多因素分析确定萎缩性胃炎是结直肠息肉的独立危险因素(OR2.294;95%CI1.597-3.296)。
结论：证实的萎缩性胃炎可能是大肠息肉的独立危险因素。
方法：在本研究中，胃镜和病理诊断为萎缩性胃炎和肠息肉。这项回顾性研究中的所有792例患者都根据结直肠息肉的存在分为亚组。采用卡方检验和Kruskal-Wallis检验分析息肉与萎缩性胃炎的相关性。采用受试者工作特征(ROC)曲线比较Hp感染与萎缩性胃炎对结直肠息肉的预测价值。采用二元Logistic回归分析确定结直肠息肉的独立危险因素。
结果：结直肠息肉患者主要为高龄男性，结直肠息肉患者的数量与吸烟有更高的相关性，饮酒,而Hp感染组优于对照组。观察到大肠息肉的数量与萎缩性胃炎的严重程度呈正相关。ROC分析显示萎缩性胃炎是大肠息肉较好的危险因素。多因素分析确定萎缩性胃炎是结直肠息肉的独立危险因素(OR2.294;95%CI1.597-3.296)。
结论：证实的萎缩性胃炎可能是大肠息肉的独立危险因素。
