Abstract：
Intracranial collision tumor is a rare entity that represents the coexistence of two histopathological different tumor types in the same area without histological admixture or an intermediate cell population zone. So far, several cases of collision tumors with ganglioglioma as its component have been reported in the literature, while supratentorial ependymoma has never been reported as a collision tumor component. We are presenting a unique case of collision tumor in patient without previous history of head trauma, neurological surgery, radiotherapy, or phakomatosis.
A 17-year-old male with no previous history of head trauma, neurological surgery, radiotherapy, or phakomatosis was presented to our clinic with grand mal seizure. Brain magnetic resonance imaging with gadolinium contrast was done revealing a contrast-enhancing lesion of right frontal lobe closely related to dura, surrounded by perifocal edema. The patient underwent a gross total tumor resection. Histological examination revealed collision tumor with two distinct components: ganglioglioma and supratentorial ependymoma.
To our best knowledge, no previous reports of collision tumor composed of ganglioglioma and supratentorial ependymoma in a single patient have been reported. We believe that this report could significantly contribute to further surgical practice as well as to treatment decision for these types of collision tumors.
A 17-year-old male with no previous history of head trauma, neurological surgery, radiotherapy, or phakomatosis was presented to our clinic with grand mal seizure. Brain magnetic resonance imaging with gadolinium contrast was done revealing a contrast-enhancing lesion of right frontal lobe closely related to dura, surrounded by perifocal edema. The patient underwent a gross total tumor resection. Histological examination revealed collision tumor with two distinct components: ganglioglioma and supratentorial ependymoma.
To our best knowledge, no previous reports of collision tumor composed of ganglioglioma and supratentorial ependymoma in a single patient have been reported. We believe that this report could significantly contribute to further surgical practice as well as to treatment decision for these types of collision tumors.
摘要：
目的：颅内碰撞肿瘤是一种罕见的实体，代表两种组织病理学不同的肿瘤类型在同一区域共存，而没有组织学混合或中间细胞群区。到目前为止,在文献中已经报道了几例以神经节胶质瘤为组成部分的碰撞肿瘤，而幕上室管膜瘤从未被报道为碰撞肿瘤成分。我们正在为没有头部外伤史的患者提供一个独特的碰撞肿瘤病例，神经外科手术,放射治疗,或phokomatosis。
结果：一名17岁男性，既往无头部外伤史，神经外科手术,放射治疗,或phakomatosis因癫痫大发作而出现在我们的诊所。用钆对比剂进行脑磁共振成像，发现与硬脑膜密切相关的右额叶对比剂增强病变，周围是局灶性水肿.患者接受了大体全肿瘤切除术。组织学检查显示碰撞肿瘤具有两个不同的组成部分：神经节胶质瘤和幕上室管膜瘤。
结论：据我们所知，以前没有报道单个患者的由神经节胶质瘤和幕上室管膜瘤组成的碰撞肿瘤。我们认为，该报告可以为这些类型的碰撞肿瘤的进一步手术实践以及治疗决策做出重大贡献。
结果：一名17岁男性，既往无头部外伤史，神经外科手术,放射治疗,或phakomatosis因癫痫大发作而出现在我们的诊所。用钆对比剂进行脑磁共振成像，发现与硬脑膜密切相关的右额叶对比剂增强病变，周围是局灶性水肿.患者接受了大体全肿瘤切除术。组织学检查显示碰撞肿瘤具有两个不同的组成部分：神经节胶质瘤和幕上室管膜瘤。
结论：据我们所知，以前没有报道单个患者的由神经节胶质瘤和幕上室管膜瘤组成的碰撞肿瘤。我们认为，该报告可以为这些类型的碰撞肿瘤的进一步手术实践以及治疗决策做出重大贡献。
