Abstract：
Canine thyroid carcinomas are relatively common malignant endocrine neoplasms in dogs derived from either thyroid follicular cells (forming follicular thyroid carcinomas) or medullary cells (parafollicular, C-cells; forming medullary thyroid carcinomas). Older and recent clinical studies often fail to discriminate between compact cellular (solid) follicular thyroid carcinomas and medullary thyroid carcinomas, which may skew conclusions. The compact subtype of follicular thyroid carcinomas appears to be the least differentiated subtype of follicular thyroid carcinomas and needs to be differentiated from medullary thyroid carcinomas. This review includes information on the signalment, presentation, etiopathogenesis, classification, histologic and immunohistochemical diagnosis, clinical management, and biochemical and genetic derangements of canine follicular and medullary carcinomas, and their correlates with human medicine.
摘要：
犬甲状腺癌是犬中相对常见的恶性内分泌肿瘤，来自甲状腺滤泡细胞（形成滤泡性甲状腺癌）或髓样细胞（滤泡旁，C细胞；形成甲状腺髓样癌）。较早和最近的临床研究通常无法区分致密细胞（固体）滤泡性甲状腺癌和髓样甲状腺癌，这可能会扭曲结论。滤泡性甲状腺癌的紧凑亚型似乎是滤泡性甲状腺癌的分化程度最低的亚型，需要与髓样甲状腺癌区分开。这项审查包括有关该标志的信息，介绍,病因，分类，组织学和免疫组织化学诊断，临床管理，犬滤泡癌和髓样癌的生化和遗传紊乱，它们与人类医学有关。
