PDF(Pubmed)
Abstract：
UNASSIGNED: To discuss the clinical value of hepatic and portal vein Doppler ultrasounds in assessing liver inflammation and fibrosis in patients with chronic hepatitis B virus (HBV) infection, and a normal alanine transaminase (ALT) level.
UNASSIGNED: 94 patients with chronic HBV infections who had undergone ultrasound-guided liver biopsies were enrolled and grouped by the liver tissue pathological results. Analyzed the differences and correlation between parameters of the hepatic and portal vein Doppler ultrasounds are discussed across different degrees of liver inflammation and fibrosis.
UNASSIGNED: There were 27 patients with no significant liver damage and 67 patients with significant liver damage, there were significant differences in the parameters of the hepatic and portal vein Doppler ultrasounds between them (p < 0.05). As liver inflammation was aggravated, the inner diameter of the portal vein increased, and the blood flow velocities of the portal and superior mesenteric veins decreased (p < 0.05). When liver fibrosis became more severe, the inner diameter of the portal vein increased, while the blood flow velocities of the portal, superior mesenteric, and splenic veins decreased, and the Doppler waveforms of hepatic veins became unidirectional or flat (p < 0.05). The receiver operating characteristic (ROC) curve showed the assessment efficacy of hepatic and portal vein Doppler ultrasounds was superior to abdominal Doppler ultrasound alone in assessing liver fibrosis, and the combination of the two examination techniques outperformed any technique used alone.
UNASSIGNED: The hepatic and portal vein Doppler ultrasounds have important clinical value for assessing liver fibrosis in patients with chronic HBV infection, to aid improve the diagnosis of liver fibrosis.
UNASSIGNED: 94 patients with chronic HBV infections who had undergone ultrasound-guided liver biopsies were enrolled and grouped by the liver tissue pathological results. Analyzed the differences and correlation between parameters of the hepatic and portal vein Doppler ultrasounds are discussed across different degrees of liver inflammation and fibrosis.
UNASSIGNED: There were 27 patients with no significant liver damage and 67 patients with significant liver damage, there were significant differences in the parameters of the hepatic and portal vein Doppler ultrasounds between them (p < 0.05). As liver inflammation was aggravated, the inner diameter of the portal vein increased, and the blood flow velocities of the portal and superior mesenteric veins decreased (p < 0.05). When liver fibrosis became more severe, the inner diameter of the portal vein increased, while the blood flow velocities of the portal, superior mesenteric, and splenic veins decreased, and the Doppler waveforms of hepatic veins became unidirectional or flat (p < 0.05). The receiver operating characteristic (ROC) curve showed the assessment efficacy of hepatic and portal vein Doppler ultrasounds was superior to abdominal Doppler ultrasound alone in assessing liver fibrosis, and the combination of the two examination techniques outperformed any technique used alone.
UNASSIGNED: The hepatic and portal vein Doppler ultrasounds have important clinical value for assessing liver fibrosis in patients with chronic HBV infection, to aid improve the diagnosis of liver fibrosis.
摘要：
■探讨肝脏和门静脉多普勒超声在评估慢性乙型肝炎病毒（HBV）感染患者肝脏炎症和纤维化中的临床价值。和正常的丙氨酸转氨酶（ALT）水平。
■94例接受超声引导肝活检的慢性HBV感染患者被纳入并按肝组织病理结果分组。分析了肝脏和门静脉多普勒超声参数之间的差异和相关性，讨论了不同程度的肝脏炎症和纤维化。
■27例无明显肝损害,67例明显肝损害,肝脏和门静脉多普勒超声参数之间存在显着差异（p<0.05）。随着肝脏炎症的加重，门静脉内径增大,门静脉和肠系膜上静脉的血流速度降低（p<0.05）。当肝纤维化变得更严重时，门静脉内径增大,而入口的血流速度，肠系膜上,脾静脉减少,肝静脉的多普勒波形变为单向或平坦（p<0.05）。受试者工作特征(ROC)曲线显示肝、门静脉多普勒超声评价肝纤维化疗效优于单纯腹部多普勒超声,并且两种检查技术的组合优于任何单独使用的技术。
■肝和门静脉多普勒超声对慢性HBV感染患者肝纤维化评估具有重要的临床价值，以帮助提高肝纤维化的诊断。
■94例接受超声引导肝活检的慢性HBV感染患者被纳入并按肝组织病理结果分组。分析了肝脏和门静脉多普勒超声参数之间的差异和相关性，讨论了不同程度的肝脏炎症和纤维化。
■27例无明显肝损害,67例明显肝损害,肝脏和门静脉多普勒超声参数之间存在显着差异（p<0.05）。随着肝脏炎症的加重，门静脉内径增大,门静脉和肠系膜上静脉的血流速度降低（p<0.05）。当肝纤维化变得更严重时，门静脉内径增大,而入口的血流速度，肠系膜上,脾静脉减少,肝静脉的多普勒波形变为单向或平坦（p<0.05）。受试者工作特征(ROC)曲线显示肝、门静脉多普勒超声评价肝纤维化疗效优于单纯腹部多普勒超声,并且两种检查技术的组合优于任何单独使用的技术。
■肝和门静脉多普勒超声对慢性HBV感染患者肝纤维化评估具有重要的临床价值，以帮助提高肝纤维化的诊断。
