PDF(Pubmed)
Abstract：
Although ocular findings in diabetic patients are well described, prevalence data for those is unknown.
To describe the prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus.
Medical records from diabetic dogs assessed by the ophthalmology and the internal medicine services at the Veterinary Teaching Hospital of the Autonomous University of Barcelona were reviewed (2009-2019).
Seventy-five dogs (150 eyes) of both genders (51/75 females; 68% and 24/75 males; 32%) and a mean age of 9.37 ± 2.43 years, were included. The most common ocular findings were cataracts (146/150; 97.3%), vitreous degeneration (45/98; 45.9%), anterior uveitis (47/150; 31.3%), aqueous deficiency dry eye (ADDE) (33/150; 22%), diffuse corneal edema (31/150; 20.7%), non-proliferative retinopathy (13/98; 13.3%), and lipid keratopathy (9/150; 6%). The most prevalent type of cataracts observed (78/146; 53.4%) was intumescent, which was commonly accompanied by non-proliferative retinopathy (p = 0.003). Among the diabetic dogs, blood glucose levels were statistically higher in dogs with non-proliferative retinopathy or anterior uveitis (p < 0.005).
Ocular complications of diabetes mellitus in dogs are numerous, being the most frequent intumescent cataracts, vitreous degeneration, anterior uveitis, ADDE, diffuse corneal edema, and non-proliferative retinopathy. This high prevalence warrants a more detailed ophthalmic evaluation in diabetic dogs especially for those undergoing cataract surgery. Furthermore, a predisposition for anterior segment inflammation and non-proliferative retinopathy is suggested when fasting plasma glucose is higher than 600 mg/dl..
To describe the prevalence of ocular findings and their association with glycemia in dogs with diabetes mellitus.
Medical records from diabetic dogs assessed by the ophthalmology and the internal medicine services at the Veterinary Teaching Hospital of the Autonomous University of Barcelona were reviewed (2009-2019).
Seventy-five dogs (150 eyes) of both genders (51/75 females; 68% and 24/75 males; 32%) and a mean age of 9.37 ± 2.43 years, were included. The most common ocular findings were cataracts (146/150; 97.3%), vitreous degeneration (45/98; 45.9%), anterior uveitis (47/150; 31.3%), aqueous deficiency dry eye (ADDE) (33/150; 22%), diffuse corneal edema (31/150; 20.7%), non-proliferative retinopathy (13/98; 13.3%), and lipid keratopathy (9/150; 6%). The most prevalent type of cataracts observed (78/146; 53.4%) was intumescent, which was commonly accompanied by non-proliferative retinopathy (p = 0.003). Among the diabetic dogs, blood glucose levels were statistically higher in dogs with non-proliferative retinopathy or anterior uveitis (p < 0.005).
Ocular complications of diabetes mellitus in dogs are numerous, being the most frequent intumescent cataracts, vitreous degeneration, anterior uveitis, ADDE, diffuse corneal edema, and non-proliferative retinopathy. This high prevalence warrants a more detailed ophthalmic evaluation in diabetic dogs especially for those undergoing cataract surgery. Furthermore, a predisposition for anterior segment inflammation and non-proliferative retinopathy is suggested when fasting plasma glucose is higher than 600 mg/dl..
摘要：
■尽管糖尿病患者的眼部表现得到了很好的描述，这些患者的患病率数据未知。
■描述糖尿病犬的眼部发现的患病率及其与血糖的关联。
■回顾了巴塞罗那自治大学兽医教学医院眼科和内科服务评估的糖尿病犬的病历（2009-2019年）。
■男女75只狗（150只眼）（雌性51/75；68％和雄性24/75；32％），平均年龄为9.37±2.43岁，包括在内。最常见的眼部表现是白内障（146/150；97.3%），玻璃体变性(45/98;45.9%),前葡萄膜炎(47/150;31.3%),房水缺乏干眼（ADDE）（33/150；22％），弥漫性角膜水肿（31/150；20.7%），非增生性视网膜病变（13/98;13.3%），和脂质角膜病变（9/150;6%）。观察到的最普遍的白内障类型（78/146;53.4％）是膨胀型，常伴有非增生性视网膜病变（p=0.003）。在糖尿病犬中，非增生性视网膜病变或前葡萄膜炎犬的血糖水平在统计学上较高(p<0.005).
■狗的糖尿病眼部并发症很多，作为最常见的膨胀型白内障，玻璃体变性,前葡萄膜炎,ADDE,弥漫性角膜水肿,和非增殖性视网膜病变。这种高患病率需要对糖尿病犬进行更详细的眼科评估，尤其是对接受白内障手术的犬。此外，当空腹血糖高于600mg/dl时，提示有眼前段炎症和非增生性视网膜病变的倾向。.
■描述糖尿病犬的眼部发现的患病率及其与血糖的关联。
■回顾了巴塞罗那自治大学兽医教学医院眼科和内科服务评估的糖尿病犬的病历（2009-2019年）。
■男女75只狗（150只眼）（雌性51/75；68％和雄性24/75；32％），平均年龄为9.37±2.43岁，包括在内。最常见的眼部表现是白内障（146/150；97.3%），玻璃体变性(45/98;45.9%),前葡萄膜炎(47/150;31.3%),房水缺乏干眼（ADDE）（33/150；22％），弥漫性角膜水肿（31/150；20.7%），非增生性视网膜病变（13/98;13.3%），和脂质角膜病变（9/150;6%）。观察到的最普遍的白内障类型（78/146;53.4％）是膨胀型，常伴有非增生性视网膜病变（p=0.003）。在糖尿病犬中，非增生性视网膜病变或前葡萄膜炎犬的血糖水平在统计学上较高(p<0.005).
■狗的糖尿病眼部并发症很多，作为最常见的膨胀型白内障，玻璃体变性,前葡萄膜炎,ADDE,弥漫性角膜水肿,和非增殖性视网膜病变。这种高患病率需要对糖尿病犬进行更详细的眼科评估，尤其是对接受白内障手术的犬。此外，当空腹血糖高于600mg/dl时，提示有眼前段炎症和非增生性视网膜病变的倾向。.
