Meta-analysis of randomized controlled trials.
Postoperative care.
Perioperative regional anesthesia.
Adults undergoing thoracic surgery.
The primary outcome was total QoR scores 24 hours after surgery. Secondary outcomes were postoperative opioid consumption, pain scores, pulmonary function, respiratory complications, and other adverse effects. Eight studies were identified, of which 6 involving 532 patients receiving video-assisted thoracic surgery were included in the quantitative analysis of QoR. Regional anesthesia significantly improved QoR-40 score (mean difference 9.48; 95% CI 3.53-15.44; I2 = 89%; 4 trials involving 296 patients) and QoR-15 score (mean difference 6.7; 95% CI 2.58-10.82; I2 = 0%; 2 trials involving 236 patients). Regional anesthesia also significantly reduced postoperative opioid consumption and the incidence of nausea and vomiting. Insufficient data were available to meta-analyze the effects of regional anesthesia on postoperative pulmonary function or respiratory complications.
The available evidence suggests that regional anesthesia can enhance QoR after video-assisted thoracic surgery. Future studies should confirm and extend these findings.
方法:随机对照试验的Meta分析。
方法:术后护理。
方法:围手术期区域麻醉。
方法:成人胸外科手术。
结果:主要结果是手术后24小时的总QoR评分。次要结果是术后阿片类药物的消耗,疼痛评分,肺功能,呼吸系统并发症,和其他不良影响。确定了八项研究,其中6例,涉及532例接受电视胸腔镜手术的患者被纳入QoR的定量分析。区域麻醉显著改善了QoR-40评分(平均差9.48;95%CI3.53-15.44;I2=89%;4项试验涉及296例患者)和QoR-15评分(平均差6.7;95%CI2.58-10.82;I2=0%;2项试验涉及236例患者)。区域麻醉还可以显着降低术后阿片类药物的消耗以及恶心和呕吐的发生率。没有足够的数据来荟萃分析区域麻醉对术后肺功能或呼吸系统并发症的影响。
结论:现有证据表明,区域麻醉可以提高胸腔镜手术后的QoR。未来的研究应该证实并扩展这些发现。