Abstract：
Bone marrow transplant and haemato-oncology patients are at risk of healthcare-associated infections due to waterborne pathogens. We undertook a narrative review of waterborne outbreaks in haemato-oncology patients from 2000 to 2022. Databases searched included PubMed, DARE and CDSR, and were undertaken by two authors. We analysed the organisms implicated, sources identified and infection prevention and control strategies implemented. The most commonly implicated pathogens were Pseudomonas aeruginosa, non-tuberculous mycobacteria and Legionella pneumophila. Bloodstream infection was the most common clinical presentation. The majority of incidents employed multi-modal strategies to achieve control, addressing both the water source and routes of transmission. This review highlights the risk to haemato-oncology patients from waterborne pathogens and discusses future preventative strategies and the requirement for new UK guidance for haemato-oncology units.
摘要：
骨髓移植和血液肿瘤患者由于水传播的病原体而面临医疗保健相关感染的风险。我们对2000-2022年血液肿瘤患者的水传播暴发进行了叙述性回顾。搜索的数据库包括Pubmed、DARE和CDSR由两名作者承担。我们分析了所涉及的生物，确定感染源并实施感染预防和控制策略。最常见的病原体是铜绿假单胞菌，非结核分枝杆菌和嗜肺军团菌。血流感染是最常见的临床表现。大多数事件采用多式联运策略来实现控制，解决水源和传播途径。这篇综述强调了水传播病原体对血液肿瘤患者的风险，并讨论了未来的预防策略以及英国对血液肿瘤单位的新指南的要求。
