PDF(Pubmed)
Abstract：
Several countries in the European Union (EU) and European Economic Area (EEA) established and/or scaled up HIV pre-exposure prophylaxis (PrEP) programmes between 2016 and 2023. Data on PrEP programmes\' performance and effectiveness in reaching those most in need will be needed to assess regional progress in the roll-out of PrEP. However, there is a lack of commonly defined indicators for routine monitoring to allow for minimum comparability. We propose a harmonised PrEP monitoring approach for the EU/EEA, based on a systematic and evidence-informed consensus-building process involving a broad and multidisciplinary expert panel. We present a set of indicators, structured along relevant steps of an adapted PrEP care continuum, and offer a prioritisation based on the degree of consensus among the expert panel. We distinguish between \'core\' indicators deemed essential for any PrEP programme in the EU/EEA, vs \'supplementary\' and \'optional\' indicators that provide meaningful data, yet where experts evaluated their feasibility for data collection and reporting as very context-dependent. By combining a standardised approach with strategic opportunities for adaptation and complementary research, this monitoring framework will contribute to assess the impact of PrEP on the HIV epidemic in Europe.
摘要：
欧盟（EU）和欧洲经济区（EEA）的几个国家在2016年至2023年之间建立和/或扩大了艾滋病毒暴露前预防（PrEP）计划。将需要有关PrEP计划的绩效和有效性的数据，以评估在推广PrEP方面的区域进展。然而,缺乏常规监测的普遍定义的指标，以允许最低限度的可比性。我们为欧盟/欧洲经济区提出了一种统一的PrEP监测方法，基于一个系统和有证据的共识建立过程，该过程涉及一个广泛和多学科的专家小组。我们提出了一套指标，按照适应的PrEP护理连续体的相关步骤构建，并根据专家小组之间的共识程度提供优先级。我们区分了被认为对欧盟/欧洲经济区的任何PrEP计划至关重要的“核心”指标，与提供有意义数据的\'补充\'和\'可选\'指标，然而，专家们评估了他们数据收集和报告的可行性，认为这是非常依赖于环境的。通过将标准化方法与适应和补充研究的战略机会相结合，这一监测框架将有助于评估PrEP对欧洲艾滋病毒流行的影响.
