PDF(Pubmed)
Abstract：
The treatment of glottic cancer remains challenging, especially with regard to morbidity reduction and larynx preservation rates. The National Comprehensive Cancer Network (NCCN) has published guidelines to aid decision-making about this treatment according to the tumor site, clinical stage, and patient medical status.
The present review was conducted to identify changes in the NCCN guidelines for glottic cancer treatment made between 2011 and 2022 and to describe the published evidence concerning glottic cancer treatment and oncological outcomes in the same time period.
Clinical practice guidelines for head and neck cancer published from 2011 up to 2022 were obtained from the NCCN website (www.NCCN.org). Data on glottic cancer treatment recommendations were extracted, and descriptive analysis was performed. In addition, a review of literature registered in the PubMed database was performed to obtain data on glottic cancer management protocols and treatment outcomes from randomized controlled trials, systematic reviews, and meta-analyses published from 2011 to 2022. In total, 24 NCCN guidelines and updates and 68 relevant studies included in the PubMed database were identified. The main guideline changes made pertained to surgical and systemic therapies, the consideration of adverse features, and new options for the treatment of metastatic disease at initial presentation. Early-stage glottic cancer received the most research attention, with transoral endoscopic laser surgery and radiotherapy assessed and compared as the main treatment modalities. Reported associations between treatment types and survival rates for this stage of glottic cancer appear to be similar, but functional outcomes can be highly compromised.
NCCN panel members provide updated recommendations based on currently accepted treatment approaches for glottic cancer, constantly reviewing new surgical and non-surgical techniques. The guidelines support decision-making about glottic cancer treatment that should be individualized and prioritize patients\' quality of life, functionality, and preferences.
The present review was conducted to identify changes in the NCCN guidelines for glottic cancer treatment made between 2011 and 2022 and to describe the published evidence concerning glottic cancer treatment and oncological outcomes in the same time period.
Clinical practice guidelines for head and neck cancer published from 2011 up to 2022 were obtained from the NCCN website (www.NCCN.org). Data on glottic cancer treatment recommendations were extracted, and descriptive analysis was performed. In addition, a review of literature registered in the PubMed database was performed to obtain data on glottic cancer management protocols and treatment outcomes from randomized controlled trials, systematic reviews, and meta-analyses published from 2011 to 2022. In total, 24 NCCN guidelines and updates and 68 relevant studies included in the PubMed database were identified. The main guideline changes made pertained to surgical and systemic therapies, the consideration of adverse features, and new options for the treatment of metastatic disease at initial presentation. Early-stage glottic cancer received the most research attention, with transoral endoscopic laser surgery and radiotherapy assessed and compared as the main treatment modalities. Reported associations between treatment types and survival rates for this stage of glottic cancer appear to be similar, but functional outcomes can be highly compromised.
NCCN panel members provide updated recommendations based on currently accepted treatment approaches for glottic cancer, constantly reviewing new surgical and non-surgical techniques. The guidelines support decision-making about glottic cancer treatment that should be individualized and prioritize patients\' quality of life, functionality, and preferences.
摘要：
背景：声门癌的治疗仍然具有挑战性，特别是在降低发病率和喉部保存率方面。国家综合癌症网络（NCCN）发布了指南，以帮助根据肿瘤部位做出有关这种治疗的决策。临床分期,和病人的医疗状况。
目的：本综述旨在确定2011年至2022年间制定的NCCN声门癌治疗指南的变化，并描述同期已发表的有关声门癌治疗和肿瘤学结果的证据。
结果：从NCCN网站获得了2011年至2022年发布的头颈癌临床实践指南（www。NCCN.org)。提取了有关声门癌治疗建议的数据，并进行描述性分析。此外,我们对PubMed数据库中注册的文献进行了综述，以获得来自随机对照试验的声门癌治疗方案和治疗结果的数据。系统评价,和2011年至2022年发表的荟萃分析。总的来说,确定了PubMed数据库中包含的24项NCCN指南和更新以及68项相关研究。与手术和全身治疗有关的主要指南更改，考虑不利特征，以及在初次出现时治疗转移性疾病的新选择。早期声门癌受到了最多的研究关注，经口内镜激光手术和放疗作为主要治疗方式进行评估和比较。据报道，该阶段声门癌的治疗类型和生存率之间的关联似乎相似，但是功能结果可能会受到很大损害。
结论：NCCN小组成员根据目前接受的声门癌治疗方法提供了最新建议，不断审查新的手术和非手术技术。该指南支持声门癌治疗的决策，这些决策应个体化，并优先考虑患者的生活质量。功能，和偏好。
目的：本综述旨在确定2011年至2022年间制定的NCCN声门癌治疗指南的变化，并描述同期已发表的有关声门癌治疗和肿瘤学结果的证据。
结果：从NCCN网站获得了2011年至2022年发布的头颈癌临床实践指南（www。NCCN.org)。提取了有关声门癌治疗建议的数据，并进行描述性分析。此外,我们对PubMed数据库中注册的文献进行了综述，以获得来自随机对照试验的声门癌治疗方案和治疗结果的数据。系统评价,和2011年至2022年发表的荟萃分析。总的来说,确定了PubMed数据库中包含的24项NCCN指南和更新以及68项相关研究。与手术和全身治疗有关的主要指南更改，考虑不利特征，以及在初次出现时治疗转移性疾病的新选择。早期声门癌受到了最多的研究关注，经口内镜激光手术和放疗作为主要治疗方式进行评估和比较。据报道，该阶段声门癌的治疗类型和生存率之间的关联似乎相似，但是功能结果可能会受到很大损害。
结论：NCCN小组成员根据目前接受的声门癌治疗方法提供了最新建议，不断审查新的手术和非手术技术。该指南支持声门癌治疗的决策，这些决策应个体化，并优先考虑患者的生活质量。功能，和偏好。
