Abstract：
Background: Odontogenic infections are common and self-limiting in most cases; however, they can lead to severe consequences, considerable morbidity and can even be fatal despite modern medical therapy. Patients and Methods: This retrospective study included patients with severe deep fascial space infections treated in the Maxillofacial Surgery Unit, General Surgery Department, Faculty of Medicine, Sohag University, Sohag Governorate, Egypt, and the Department of Oral and Maxillofacial Surgery, King Fahd Specialist Hospital (tertiary referral center), Burayda City, Qassim Province, Saudi Arabia, from June 2017 to June 2022. Results: This study included 296 patients, 161 (54.4%) males, 135 (45.6%) females. The fifth decade of life was the most common vulnerable age group. Forty-three percent of patients had diabetes mellitus, 26.6% were hypertensive, and 13.3% were on long-term steroid therapy. In 83% of patients, the offending tooth was identified but in 17% of patients no dental cause was identified. The lower third molar tooth was most commonly involved. Sixty-nine (23.3%) patients had submandibular space infections. Fifty-three (17.9%) patients had canine space infections. Thirty (10.1%) patients had submasseteric space infection. Twenty-eight (9.5%) patients had submental space infections. Twenty-three (7.8%) patients had combined infection of the submasseteric, submandibular, and pterygomandibular spaces, whereas 19 (6.4%) patients presented with Ludwig\'s angina. Conclusions: Odontogenic infections are common. The submandibular space is the most commonly affected single space. These infections could lead to lethal complications in immunocompromised patients, especially patients with diabetes mellitus. These infections require urgent surgical intervention to decrease hospital stays and avoid potentially lethal complications.
摘要：
背景：牙源性感染在大多数情况下是常见的和自限性的；然而，会导致严重的后果,相当高的发病率，甚至可能是致命的，尽管现代医学治疗。患者和方法：这项回顾性研究包括颌面外科治疗的严重深筋膜间隙感染患者，普外科,医学院,Sohag大学，Sohag省,埃及,和口腔颌面外科，法赫德国王专科医院（三级转诊中心），Burayda市,卡西姆省,沙特阿拉伯,从2017年6月到2022年6月。结果：本研究共纳入296例患者，男性161人（54.4%），女性135人（45.6%）。生命的第五个十年是最常见的脆弱年龄组。43%的患者患有糖尿病，26.6%为高血压,13.3%接受长期类固醇治疗.在83％的患者中，发现了有问题的牙齿，但在17％的患者中，没有发现牙齿原因。最常见的是下第三磨牙。69例（23.3％）患者存在颌下间隙感染。53例（17.9％）患者患有犬间隙感染。30例（10.1％）患者发生了咬下间隙感染。28例（9.5％）患者患有下间隙感染。23例(7.8%)患者出现咬肌下联合感染,颌下,翼状下颌空间，而19例（6.4%）患者出现路德维希心绞痛。结论：牙源性感染很常见。颌下间隙是最常见的单个空间。这些感染可能导致免疫功能低下患者的致命并发症，尤其是糖尿病患者。这些感染需要紧急手术干预以减少住院时间并避免潜在的致命并发症。
